Feelings of hunger and satiety are the key determinants for maintaining the life of humans
and animals. Disturbed appetite control may disrupt the metabolic health of the host and …

Background Obesity develops due to an imbalance in energy homeostasis, wherein energy
intake exceeds energy expenditure. Accumulating evidence shows that manipulations of …

Micronutrient deficiency is a major cause of disease throughout the world. Yet, how
perturbations influence the immune-microbiome interface remains poorly understood. Here …

Integrated immunometabolic responses link dietary intake, energy utilization, and storage to
immune regulation of tissue function and is therefore essential for the maintenance and …

Aging is the greatest risk factor for most diseases including cancer, cardiovascular disorders,
and neurodegenerative disease. There is emerging evidence that interventions that improve …

Dietary proteins have been used for years to treat obesity. Body weight loss is beneficial
when it concerns fat mass, but loss of fat free mass–especially muscle might be detrimental …

Aging is a modifiable risk factor for most chronic diseases and an inevitable process in
humans. The development of pharmacological interventions aimed at delaying or preventing …

Both life span and health span are influenced by genetic, environmental and lifestyle factors.
With the genetic influence on human life span estimated to be about 20–25%, epigenetic …

The prevalence of obesity is a worldwide phenomenon in all age groups and is associated
with aging-related diseases such as type 2 diabetes, as well metabolic and cardiovascular …

The role of the microbiome in health and disease has gained considerable attention and
shed light on the etiology of complex diseases like inflammatory bowel disease (IBD) and …