Nano-medicine and vascular endothelial dysfunction: options and delivery strategies

G Taneja, A Sud, N Pendse, B Panigrahi… - Cardiovascular …, 2019 - Springer
The endothelium is a thin innermost layer of flat cells which release various mediators
including endothelin-1 (ET-1), prostanoids, von Willebrand factor (vWF) and endothelium …

S-nitrosoglutathione reductase–dependent PPARγ denitrosylation participates in MSC-derived adipogenesis and osteogenesis

Y Cao, SA Gomes, EB Rangel… - The Journal of …, 2015 - Am Soc Clin Investig
Bone marrow–derived mesenchymal stem cells (MSCs) are a common precursor of both
adipocytes and osteoblasts. While it is appreciated that PPARγ regulates the balance …

Effects of a dammarane-type saponin, ginsenoside Rd, in nicotine-induced vascular endothelial injury

B Zhang, X Hu, H Wang, R Wang, Z Sun, X Tan, S Liu… - Phytomedicine, 2020 - Elsevier
Abstract Background Panax notoginseng (Burk.) FH Chen is a traditional medicinal plant
widely used to prevent and treat cardiovascular diseases. Ginsenoside Rd (GRd) is a major …

Synthesis and preliminary therapeutic evaluation of copper nanoparticles against diabetes mellitus and-induced micro-(renal) and macro-vascular (vascular …

AK Sharma, A Kumar, G Taneja, U Nagaich, A Deep… - RSC …, 2016 - pubs.rsc.org
The current study synthesized and investigated the effect of low-dose copper nanoparticles
(CuNPs) against diabetes mellitus (streptozotocin, 50 mg kg− 1, ip, once) and-induced …

Catechin averts experimental diabetes mellitus-induced vascular endothelial structural and functional abnormalities

P Bhardwaj, D Khanna, P Balakumar - Cardiovascular toxicology, 2014 - Springer
Diabetes mellitus is associated with an induction of vascular endothelial dysfunction (VED),
an initial event that could lead to the pathogenesis of atherosclerosis and hypertension …

Dietary supplementation with fish oil alters the expression levels of proteins governing mitochondrial dynamics and prevents high-fat diet-induced endothelial …

R Sun, X Wang, Y Liu, M Xia - British journal of nutrition, 2014 - cambridge.org
Diets supplemented with fish oil (FO), which is rich in n-3 PUFA, have been shown to modify
several key risk factors for CVD. The purpose of the present study was to determine the …

Combined and individual strategy of exercise generated preconditioning and low dose copper nanoparticles serve as superlative approach to ameliorate ISO-induced …

AK Sharma, A Kumar, G Taneja, U Nagaich… - Pharmacological …, 2018 - Elsevier
Background Myocardial infarction (MI) is a solitary fatal condition with towering prevalence
of mortality worldwide. Our previous study reports that low-dose copper nanoparticles …

[HTML][HTML] The antiatherogenic effect of fish oil in male mice is associated with a diminished release of endothelial ADAM17 and ADAM10 substrates

N Speck, C Brandsch, N Schmidt, N Yazdekhasti… - The Journal of …, 2015 - Elsevier
Background: Growing evidence suggests that disintegrin and metalloprotease (ADAM) 17
(ADAM17) and ADAM10 contribute to the pathogenesis of vascular diseases. ADAM17 …

尼古丁诱发动脉粥样硬化研究进展

陈盼盼, 秦玮, 张勇 - 中国医药导报, 2015 - cqvip.com
吸烟是动脉粥样硬化的显著危险因素. 尼古丁作为烟草中的主要有害物质,
在动脉粥样硬化的发生发展中发挥重要作用. 其影响主要包括以下四个方面 …

[PDF][PDF] 血管内皮细胞来源的主要酶类及其功能

全海燕, 秦旭平 - Medical Science, 2015 - nhqks.cnjournals.com
摘摇要: 摇血管内皮细胞不仅仅在血管与血液中间起屏障作用, 而且还有分泌功能,
其功能紊乱是导致血管功能和结构改变的重要因素. 目前, 人们对血管内皮细胞所分泌的酶研究 …