HTLV-1 persistence and leukemogenesis: a game of hide-and-seek with the host immune system

BJY Tan, K Sugata, M Ono, Y Satou - Frontiers in Immunology, 2022 - frontiersin.org
Human T-cell leukemia virus type 1 (HTLV-1), a retrovirus which mainly infects CD4+ T cells
and causes adult T-cell leukemia/lymphoma (ATL), is primarily transmitted via direct cell-to …

Mechanisms of innate immune sensing of HTLV-1 and viral immune evasion

S Mohanty, EW Harhaj - Pathogens, 2023 - mdpi.com
Human T lymphotropic virus-1 (HTLV-1) was the first identified oncoretrovirus, which infects
and establishes a persistent infection in approximately 10–20 million people worldwide …

The integral membrane protein ZMPSTE24 protects cells from SARS-CoV-2 spike-mediated pseudovirus infection and syncytia formation

K Shilagardi, ED Spear, R Abraham, DE Griffin… - MBio, 2022 - Am Soc Microbiol
ABSTRACT COVID-19 pandemic caused by severe acute respiratory syndrome coronavirus
2 (SARS-CoV-2) has had a devastating impact on global public health, emphasizing the …

The helicase-like transcription factor redirects the autophagic flux and restricts human T cell leukemia virus type 1 infection

A Beauvois, H Gazon, PS Chauhan… - Proceedings of the …, 2023 - National Acad Sciences
Retroviruses and their host have coevolved in a delicate balance between viral replication
and survival of the infected cell. In this equilibrium, restriction factors expressed by infected …