Cancer remains a significant global public health concern, with increasing incidence and
mortality rates worldwide. Oxidative stress, characterized by the production of reactive …

Mitochondria play a key role in cancer and their involvement is not limited to the production
of ATP only. Mitochondria also produce reactive oxygen species and building blocks to …

Hydrogen sulfide (H2S), traditionally recognized as a toxic gas, has emerged as a critical
regulator in many biological processes, including oxidative stress and cellular homeostasis …

Simple Summary Cancer remains a major killer of the human population. Current cancer
diagnostic and therapeutic methods are associated with shortcomings of limited targetability …

Significance: Both redox and pH are important regulatory processes that underpin cell
physiological functions, in addition to influencing cancer cell development and tumor …

Significance: Redox and epigenetics are two important regulatory processes of cell
physiological functions. The cross-regulation between these processes has critical effects on …

Altered redox metabolism is one of the hallmarks of tumor cells, which not only contributes to
tumor proliferation, metastasis, and immune evasion, but also has great relevance to …

Drug resistance is currently one of the biggest challenges in cancer treatment. With the
deepening understanding of drug resistance, various mechanisms have been revealed …

Diffuse Large B-cell Lymphoma (DLBCL), with its intrinsic genetic and epigenetic
heterogeneity, exhibits significantly variable clinical outcomes among patients treated with …

Background: Resistance to standard therapeutic methods, including chemotherapy,
immunotherapy, and targeted therapy, remains a critical challenge in effective cancer …