The blood microbiome and health: current evidence, controversies, and challenges

HS Cheng, SP Tan, DMK Wong, WLY Koo… - International Journal of …, 2023 - mdpi.com
Blood is conventionally thought to be sterile. However, emerging evidence on the blood
microbiome has started to challenge this notion. Recent reports have revealed the presence …

A new horizon of precision medicine: combination of the microbiome and extracellular vesicles

J Yang, TS Shin, JS Kim, YK Jee, YK Kim - Experimental & molecular …, 2022 - nature.com
Over several decades, the disease pattern of intractable disease has changed from acute
infection to chronic disease accompanied by immune and metabolic dysfunction. In addition …

Molecular mechanism of microbiota metabolites in preterm birth: pathological and therapeutic insights

AZ Ansari, S Bose, Y You, S Park, Y Kim - International Journal of …, 2021 - mdpi.com
Preterm birth (PTB) refers to the birth of infants before 37 weeks of gestation and is a
challenging issue worldwide. Evidence reveals that PTB is a multifactorial dysregulation …

Gut and reproductive tract microbiota adaptation during pregnancy: new insights for pregnancy-related complications and therapy

M De Siena, L Laterza, MV Matteo, I Mignini, T Schepis… - Microorganisms, 2021 - mdpi.com
Pregnancy is characterized by maternal adaptations that are necessary to create a
welcoming and hospitable environment for the fetus. Studies have highlighted how the …

Oral microbiome and preterm birth

M Vidmar Šimic, A Maver, AN Zimani, K Hočevar… - Frontiers in …, 2023 - frontiersin.org
Background The etiology of preterm birth (PTB) is heterogeneous and not yet well known.
Maternal periodontal disease has been investigated for decades and is a known risk factor …

Microbiota dysbiosis and functional outcome in acute ischemic stroke patients

Y Chang, HG Woo, JH Jeong, GH Kim, KD Park… - Scientific Reports, 2021 - nature.com
Currently, few studies are reported on the composition of microbiota in stroke patients and
the association with stroke prognosis. This study investigated the differing microbiota …

Lack of evidence for microbiota in the placental and fetal tissues of rhesus macaques

KR Theis, R Romero, AD Winters, AH Jobe… - MSphere, 2020 - Am Soc Microbiol
The prevailing paradigm in obstetrics has been the sterile womb hypothesis. However, some
are asserting that the placenta, intra-amniotic environment, and fetus harbor microbial …

Association between the sinus microbiota with eosinophilic inflammation and prognosis in chronic rhinosinusitis with nasal polyps

JH Kim, SH Kim, JY Lim, D Kim, IS Jeong… - … & molecular medicine, 2020 - nature.com
Dysbiosis of the sinus microbiome affects the pathophysiology of chronic rhinosinusitis with
nasal polyps (CRSwNPs). We investigated whether the sinus microbiota in CRSwNPs is …

The pelvis urinary microbiome in patients with kidney stones and clinical associations

F Liu, N Zhang, Y Wu, P Jiang, T Jiang, Y Wang… - BMC microbiology, 2020 - Springer
Background The long-held notion that, without urinary tract or circulatory infection, bladder
urine and blood are sterile biofluids has been disproven. There have been no previous …

Identification of indicators for preterm birth using retinoid metabolites

YA You, SY Hwang, SM Kim, S Park, GI Lee, S Park… - Metabolites, 2021 - mdpi.com
Metabolites reflect the biochemical dynamics for the maintenance of pregnancy and
parturition. UPLC-Q/TOF-MS and LC-MS/MS metabolomics were performed to identify and …