We are witnessing a revolution in our understanding of primary aldosteronism (PA). In the
past 2 decades, we have learned that PA is a highly prevalent syndrome that is largely …

Context New approaches are needed to address the evolution of the primary aldosteronism
syndrome and to increase its recognition. Herein, we review evidence indicating that primary …

Background: Primary aldosteronism is a nonsuppressible renin-independent aldosterone
production that causes hypertension and cardiovascular disease. Objective: To characterize …

Background: Primary aldosteronism is a common cause of treatment-resistant hypertension.
However, evidence from local health systems suggests low rates of testing for primary …

Resistant hypertension is associated with higher rates of cardiovascular disease, kidney
disease, and death than primary hypertension. Although clinical practice guidelines …

Primary aldosteronism is an underdiagnosed cause of hypertension. Although inadequate
screening is one reason for underdiagnosis, another important contributor is that clinicians …

Primary aldosteronism (PA) is an endocrinopathy characterized by dysregulated
aldosterone production that occurs despite suppression of renin and angiotensin II, and that …

Primary aldosteronism is a common, yet highly underdiagnosed, cause of hypertension that
leads to disproportionately high rates of cardiovascular disease. Hypertension plus …

Obstructive sleep apnea (OSA) is regarded as an independent risk factor for hypertension.
The possible mechanism includes oxidative stress, endothelial injury, sympathetic …

Primary aldosteronism used to be considered a rare cause of secondary hypertension.
However, accruing evidence indicates that primary aldosteronism is more common than …