Methods for improving aptamer binding affinity
H Hasegawa, N Savory, K Abe, K Ikebukuro - Molecules, 2016 - mdpi.com
Aptamers are single stranded oligonucleotides that bind a wide range of biological targets.
Although aptamers can be isolated from pools of random sequence oligonucleotides using …
Although aptamers can be isolated from pools of random sequence oligonucleotides using …
In silico molecular docking in DNA aptamer development
Aptamers are single-stranded DNA or RNA oligonucleotides generated by SELEX that
exhibit binding affinity and specificity against a wide variety of target molecules. Compared …
exhibit binding affinity and specificity against a wide variety of target molecules. Compared …
In-Silico Selection of Aptamer Targeting SARS-CoV-2 Spike Protein
Aptamers are single-stranded, short DNA or RNA oligonucleotides that can specifically bind
to various target molecules. To diagnose the infected cases of severe acute respiratory …
to various target molecules. To diagnose the infected cases of severe acute respiratory …
Development of HGF‐binding aptamers with the combination of G4 promoter‐derived aptamer selection and in silico maturation
T Yokoyama, K Tsukakoshi, W Yoshida… - Biotechnology and …, 2017 - Wiley Online Library
We describe the selection of aptamers based on bioinformatics‐based approaches without
Systematic Evolution of Ligands by EXponential enrichment (SELEX). SELEX is a potent …
Systematic Evolution of Ligands by EXponential enrichment (SELEX). SELEX is a potent …
[PDF][PDF] Current advances and prospects on implementation of highly sensitive aptamer-based dual system for melamine detection: new promising tool of great affinity
M Omar, NJ de Dieu, M Shamoon… - Journal of Bioprocessing …, 2015 - researchgate.net
Much attention has been devoted to melamine (MA) analysis in food products in accordance
with the food safety standards. Aptamer-based analytical techniques thrived with the …
with the food safety standards. Aptamer-based analytical techniques thrived with the …
History of aptamer development
N Savory, K Abe, T Saito, K Ikebukuro - Aptamers, 2017 - taylorfrancis.com
This chapter describes Systematic evolution of ligands by exponential enrichment (SELEX)
strategies with methodological improvements, well established since the first application in …
strategies with methodological improvements, well established since the first application in …