Targeting highly proliferating cells is an important issue for many types of aggressive tumors.
Proliferating Cell Nuclear Antigen (PCNA) is an essential protein that participates in a variety …

While Next-Generation Sequencing (NGS) and technological advances have been useful in
identifying genetic profiles of tumorigenesis, novel target proteins and various clinical …

Psoriasis is a chronic inflammatory skin disease that presents increased expression of tumor
necrosis factor α (TNFα), a proinflammatory cytokine. The discovery of RNA interference …

Head and neck squamous cell carcinoma (HNSCC) still represents the world's sixth most
common tumor entity, with increasing incidence. The reachability of light makes HNSCC …

Photochemical internalization (PCI) is a promising new technology for site-specific drug
delivery, developed from photodynamic therapy (PDT). In PCI, light-induced activation of a …

Lipid nanoparticles (LNs) are widely investigated for oral drug delivery, and for achieving
significant advantages in colloidal stability, biocompatibility and scaled-up possibility …

Bacterial pathogens such as Staphylococcus aureus and Staphylococcus epidermidis can
survive in different types of cells including professional phagocytes, causing intracellular …

Bleomycin is an anticancer drug used against various types of cancers. The aim of this study
was to prepare a new PEG ylated and non‐PEG ylated nanoliposomal formulation of …

Here we evaluate the photosensitizer meso-tetraphenyl chlorin disulphonate (TPCS 2a) in
survival studies of rat glioma cancer cells in combination with the novel photochemical …

The possibility of using photochemical internalization (PCI) to enhance the effects of the
cytotoxic drug bleomycin is investigated, together with photophysical determination and …