Ghrelin, a gastric-derived acylated peptide, regulates energy homeostasis by transmitting
information about peripheral nutritional status to the brain, and is essential for protecting …

ABSTRACT Scavenger receptor A (SR-A), also known as the macrophage scavenger
receptor and cluster of differentiation 204 (CD204), plays roles in lipid metabolism …

Objective—To investigate whether and how the endoplasmic reticulum (ER) stress–induced,
CCAAT/enhancer-binding protein-homologous protein (CHOP)-mediated pathway regulates …

The only molecularly identified ghrelin receptor is the growth hormone secretagogue
receptor GHSR1a. Its natural ligand, ghrelin, is an acylated peptide whose unacylated …

Recently, we demonstrated that melatonin reduced protein kinase RNA (PKR)-like ER
kinase (PERK)-eukaryotic initiation factor 2 alpha (eIF2α)-activating transcription factor-4 …

Abstract Ischemia/reperfusion (I/R) continue to be the most frequent cause of damaged
tissues. Injured tissues resulted from the first ischemic insult, which is determined by the …

The orexigenic effect of ghrelin is mediated by neuropeptide Y (NPY) and agouti-related
protein (AgRP) in the hypothalamic arcuate nucleus (ARC). Recent evidence also indicates …

It is widely accepted that thyroid cancer is strongly determined by the individual genetic
background. In this regard, it is expected that sporadic thyroid cancer is the result of multiple …

Ghrelin, the endogenous ligand for the GH secretagogue receptor (GHSR), is a peptide
hormone with diverse physiological roles. Ghrelin regulates GH release, appetite and …

Disordered calcium homeostasis can lead to endoplasmic reticulum (ER) stress. Our
previous data showed that time course activation of ER stress contributes to time-related …