Graph signal processing, graph neural network and graph learning on biological data: a systematic review
Graph networks can model data observed across different levels of biological systems that
span from population graphs (with patients as network nodes) to molecular graphs that …
span from population graphs (with patients as network nodes) to molecular graphs that …
What value can TSPO PET bring for epilepsy treatment?
V Bouilleret, S Dedeurwaerdere - European Journal of Nuclear Medicine …, 2021 - Springer
Epilepsy is one of the most common neurological disorders and affects both the young and
adult populations. The question we asked for this review was how positron emission …
adult populations. The question we asked for this review was how positron emission …
[HTML][HTML] Effects of the T-type calcium channel CaV3. 2 R1584P mutation on absence seizure susceptibility in GAERS and NEC congenic rats models
Rationale Low-voltage-activated or T-type Ca 2+ channels play a key role in the generation
of seizures in absence epilepsy. We have described a homozygous, gain of function …
of seizures in absence epilepsy. We have described a homozygous, gain of function …
Postinjury weight rather than cognitive or behavioral impairment predicts development of posttraumatic epilepsy after lateral fluid‐percussion injury in rats
N Lapinlampi, P Andrade, T Paananen… - …, 2020 - Wiley Online Library
Objective To identify postinjury physiologic, behavioral, and cognitive biomarkers for
posttraumatic epilepsy to enrich study populations for long‐term antiepileptogenesis studies …
posttraumatic epilepsy to enrich study populations for long‐term antiepileptogenesis studies …
Toll-like Receptor 4 signaling in neurons enhances calcium-permeable α-Amino-3-Hydroxy-5-Methyl-4-isoxazolepropionic acid receptor currents and drives post …
AA Korgaonkar, Y Li, D Sekhar… - Annals of …, 2020 - escholarship.org
ObjectiveTraumatic brain injury is a major risk factor for acquired epilepsies, and
understanding the mechanisms underlying the early pathophysiology could yield viable …
understanding the mechanisms underlying the early pathophysiology could yield viable …
Pediatric traumatic brain injury and a subsequent transient immune challenge independently influenced chronic outcomes in male mice
R Sharma, PM Casillas-Espinosa, LK Dill… - Brain, behavior, and …, 2022 - Elsevier
Traumatic brain injury (TBI) is a major contributor to death and disability worldwide. Children
are at particularly high risk of both sustaining a TBI and experiencing serious long-term …
are at particularly high risk of both sustaining a TBI and experiencing serious long-term …
Effects of alpha-2 adrenergic agonist mafedine on brain electrical activity in rats after traumatic brain injury
YI Sysoev, VA Prikhodko, RT Chernyakov… - Brain Sciences, 2021 - mdpi.com
The search for and development of new neuroprotective (or cerebroprotective) drugs, as
well as suitable methods for their preclinical efficacy evaluation, are priorities for current …
well as suitable methods for their preclinical efficacy evaluation, are priorities for current …
Disease-modifying effects of a novel T-type calcium channel antagonist, Z944, in a model of temporal lobe epilepsy
PM Casillas-Espinosa, SR Shultz, EL Braine… - Progress in …, 2019 - Elsevier
We evaluated whether pharmacologically targeting T-type Ca 2+ channels with Z944, a
potent and selective antagonist, has disease-modifying effects in a model of temporal lobe …
potent and selective antagonist, has disease-modifying effects in a model of temporal lobe …
[HTML][HTML] Brain abscess–A rare confounding factor for diagnosis of post-traumatic epilepsy after lateral fluid-percussion injury
J Kyyriäinen, P Andrade, XE Ndode-Ekane… - Epilepsy Research, 2024 - Elsevier
Objective To assess the prevalence of brain abscesses as a confounding factor for the
diagnosis of post-traumatic epilepsy (PTE) in a rat model of lateral fluid-percussion-induced …
diagnosis of post-traumatic epilepsy (PTE) in a rat model of lateral fluid-percussion-induced …
Fluid-Based Protein Biomarkers in Traumatic Brain Injury: The View from the Bedside
DV Agoston, A Helmy - International Journal of Molecular Sciences, 2023 - mdpi.com
There has been an explosion of research into biofluid (blood, cerebrospinal fluid, CSF)-
based protein biomarkers in traumatic brain injury (TBI) over the past decade. The …
based protein biomarkers in traumatic brain injury (TBI) over the past decade. The …