Obstructive sleep apnea, cognition and Alzheimer's disease: a systematic review integrating three decades of multidisciplinary research

OM Bubu, AG Andrade, OQ Umasabor-Bubu… - Sleep medicine …, 2020 - Elsevier
Increasing evidence links cognitive-decline and Alzheimer's disease (AD) to various sleep
disorders, including obstructive sleep apnea (OSA). With increasing age, there are …

Connections between sleep and cognition in older adults

K Yaffe, CM Falvey, T Hoang - The Lancet Neurology, 2014 - thelancet.com
Sleep disturbances and cognitive impairment are common in older adults. Mounting
evidence points to a potential connection between sleep and cognitive function. Findings …

International consensus statement on obstructive sleep apnea

JL Chang, AN Goldberg, JA Alt… - International forum of …, 2023 - Wiley Online Library
Background Evaluation and interpretation of the literature on obstructive sleep apnea (OSA)
allows for consolidation and determination of the key factors important for clinical …

The link between obstructive sleep apnea and neurocognitive impairment: an official American thoracic society workshop report

C Lal, I Ayappa, N Ayas, AE Beaudin… - Annals of the …, 2022 - atsjournals.org
There is emerging evidence that obstructive sleep apnea (OSA) is a risk factor for preclinical
Alzheimer's disease (AD). An American Thoracic Society workshop was convened that …

Sleep apnoea and the brain: a complex relationship

I Rosenzweig, M Glasser, D Polsek… - The Lancet …, 2015 - thelancet.com
Intermittent hypoxia, reoxygenation, and hypercapnia or hypocapnia occur in both adults
and children during untreated apnoea and hypopnoea, along with changes in cerebral …

[HTML][HTML] Obstructive sleep apnea and its treatment in aging: effects on Alzheimer's disease biomarkers, cognition, brain structure and neurophysiology

AE Mullins, K Kam, A Parekh, OM Bubu, RS Osorio… - Neurobiology of …, 2020 - Elsevier
Here we review the impact of obstructive sleep apnea (OSA) on biomarkers of Alzheimer's
disease (AD) pathogenesis, neuroanatomy, cognition and neurophysiology, and present the …

Cognitive complaints in obstructive sleep apnea

TJA Vaessen, S Overeem, MM Sitskoorn - Sleep medicine reviews, 2015 - Elsevier
Obstructive sleep apnea (OSA) is associated with impairments in cognitive functioning.
Although cognitive complaints are related to quality of life, work productivity and health care …

Memory consolidation in sleep disorders

N Cellini - Sleep medicine reviews, 2017 - Elsevier
In recent years sleep-related memory consolidation has become a central topic in the sleep
research field. Several studies have shown that in healthy individuals sleep promotes …

The public health burden of obstructive sleep apnea

A Faria, AH Allen, N Fox, N Ayas, I Laher - Sleep Science, 2021 - thieme-connect.com
Obstructive sleep apnea (OSA) is the most common respiratory disorder of sleep. The vast
majority (> 80%) of adults with moderate to severe OSA remain undiagnosed. The economic …

[HTML][HTML] Obstructive sleep apnoea and Alzheimer's disease: in search of shared pathomechanisms

D Polsek, N Gildeh, D Cash… - Neuroscience & …, 2018 - Elsevier
Alzheimer's disease (AD) is a significant public health concern. The incidence continues to
rise, and it is set to be over one million in the UK by 2025. The processes involved in the …