Quantitative phase imaging: recent advances and expanding potential in biomedicine
TL Nguyen, S Pradeep, RL Judson-Torres, J Reed… - ACS …, 2022 - ACS Publications
Quantitative phase imaging (QPI) is a label-free, wide-field microscopy approach with
significant opportunities for biomedical applications. QPI uses the natural phase shift of light …
significant opportunities for biomedical applications. QPI uses the natural phase shift of light …
Live-cell mass profiling: an emerging approach in quantitative biophysics
TA Zangle, MA Teitell - Nature methods, 2014 - nature.com
Cell mass, volume and growth rate are tightly controlled biophysical parameters in cellular
development and homeostasis, and pathological cell growth defines cancer in metazoans …
development and homeostasis, and pathological cell growth defines cancer in metazoans …
Tumor cell escape from therapy-induced senescence
T Saleh, L Tyutyunyk-Massey, GF Murray… - Biochemical …, 2019 - Elsevier
H460 non-small cell lung, HCT116 colon and 4T1 breast tumor cell lines induced into
senescence by exposure to either etoposide or doxorubicin were able to recover …
senescence by exposure to either etoposide or doxorubicin were able to recover …
Drug screening at single-organoid resolution via bioprinting and interferometry
PJ Tebon, B Wang, AL Markowitz, A Davarifar… - Nature …, 2023 - nature.com
High throughput drug screening is an established approach to investigate tumor biology and
identify therapeutic leads. Traditional platforms use two-dimensional cultures which do not …
identify therapeutic leads. Traditional platforms use two-dimensional cultures which do not …
Label-free high-throughput cell screening in flow
A Mahjoubfar, C Chen, KR Niazi… - Biomedical optics …, 2013 - opg.optica.org
Flow cytometry is a powerful tool for cell counting and biomarker detection in biotechnology
and medicine especially with regards to blood analysis. Standard flow cytometers perform …
and medicine especially with regards to blood analysis. Standard flow cytometers perform …
High-speed live-cell interferometry: a new method for quantifying tumor drug resistance and heterogeneity
D Huang, KA Leslie, D Guest, O Yeshcheulova… - Analytical …, 2018 - ACS Publications
We report the development of high-speed live-cell interferometry (HSLCI), a new
multisample, multidrug testing platform for directly measuring tumor therapy response via …
multisample, multidrug testing platform for directly measuring tumor therapy response via …
Soft lithography fabrication of index-matched microfluidic devices for reducing artifacts in fluorescence and quantitative phase imaging
Microfluidic devices are widely used for biomedical applications based on microscopy or
other optical detection methods. However, the materials commonly used for microfabrication …
other optical detection methods. However, the materials commonly used for microfabrication …
LVING reveals the intracellular structure of cell growth
The continuous balance of growth and degradation inside cells maintains homeostasis.
Disturbance of this balance by internal or external factors cause state of disease, while …
Disturbance of this balance by internal or external factors cause state of disease, while …
Simultaneous measurement of neurite and neural body mass accumulation via quantitative phase imaging
Measurement of neuron behavior is crucial for studying neural development and evaluating
the impact of potential therapies on neural regeneration. Conventional approaches to …
the impact of potential therapies on neural regeneration. Conventional approaches to …
Physical cytometry: detecting mass-related properties of single cells
The physical properties of a single cell, such as mass, volume, and density, are important
indications of the cell's metabolic characteristics and homeostasis. Precise measurement of …
indications of the cell's metabolic characteristics and homeostasis. Precise measurement of …