Chronic, heavy alcohol consumption disrupts normal organ function and causes structural
damage in virtually every tissue of the body. Current diagnostic terminology states that a …

Patients with alcoholic liver disease frequently manifest clinical or histologic evidence of
cholestasis. Although cholestasis is defined as an impairment of bile excretion, it is a term …

Chronic ethanol consumption causes decreased hepatic protein degradation, resulting in
protein accumulation within hepatocytes. In this investigation, we sought to determine …

Background: A number of laboratory markers are suggested for the detection and monitoring
of alcohol abuse. However, there is still a need to find better indicators of alcohol abuse …

In order to determine whether ethanol consumption alters the targeting of hepatic lysosomal
enzymes to their organelles, we examined the sedimentation properties of lysosomal …

Endocytosis constitutes an essential process in the regulation of the expression of cell
surface molecules and receptors and, therefore, could participate in the neural-glial …

Aims: Total sialic acid (TSA) has been suggested as a marker for chronic alcohol abuse. It
seems that the elevation of TSA during excessive alcohol consumption reflects the changes …

This article represents the proceedings of a symposium at the 2000 ISBRA Meeting in
Yokohama, Japan. The chairs were Carol A. Casey and Amin Nanji. The presentations were …

Chronic ethanol administration markedly impairs the process of receptor‐mediated
endocytosis (RME) of a representative asialoglycoprotein, asialoorosomucoid (ASOR), by …

During receptor-mediated endocytosis (RME), extracellular molecules are internalized after
being recognized and bound to specific cell surface receptors. In previous studies of the …