Background Allogeneic hematopoietic stem cell transplantation (HSCT) can expose patients
to a transient but marked immunosuppression, during which viral infections are an important …

Natural killer (NK) cells play an important role in surveillance and elimination of malignant
cells. Their spontaneous cytotoxicity was first demonstrated in vitro against leukemia cell …

Background Anti-thymocyte globulin (ATG) was introduced into the conditioning regimen in
haemopoietic cell transplantation (HCT) to prevent graft-versus-host-disease (GvHD) and …

Successful immune reconstitution (IR) is associated with improved outcomes following
pediatric cord blood transplantation (CBT). Usage and timing of anti–thymocyte globulin …

Although cytomegalovirus (CMV) reactivation has long been implicated in posttransplant
immune dysfunction, the molecular mechanisms that drive this phenomenon remain …

Viral reactivation occurs frequently in the context of immunodeficiency and
immunosuppression after allogeneic hematopoietic stem cell transplantation (allo-HSCT) …

Background Viral reactivations (VRs) after hematopoietic cell transplantation (HCT)
contribute to significant morbidity and mortality. Timely immune reconstitution (IR) is …

Delayed immune reconstitution after hematopoietic stem cell transplantation (HSCT) has
been associated with significant morbidity and mortality, especially after allogeneic HSCT …

Controversy surrounds the potential association between cytomegalovirus (CMV) infection
and increased risk of mortality after allogeneic hematopoietic stem cell transplantation (Allo …

Childhood cancer and its treatment often impact the haematopoietic and lymphatic systems,
with immunological consequences. Immunological assessments are not routinely included …