Advances in artificial intelligence are stimulating interest in neuroscience. However, most
attention is given to discrete tasks with simple action spaces, such as board games and …

Stroke affects one out of every six people on Earth. Approximately 90% of stroke survivors
have some functional disability with mobility being a major impairment, which not only …

Brain-machine interfaces (BMIs) provide a new assistive strategy aimed at restoring mobility
in severely paralyzed patients. Yet, no study in animals or in human subjects has indicated …

With efficiencies derived from evolution, growth and learning, humans are very well-tuned
for locomotion 1. Metabolic energy used during walking can be partly replaced by power …

Evidence suggests that the nervous system controls motor tasks using a low-dimensional
modular organization of muscle activation. However, it is not clear if such an organization …

Each of the descending pathways involved in motor control has a number of anatomical,
molecular, pharmacological, and neuroinformatic characteristics. They are differentially …

While neuroscientists identify increasingly complex neural circuits that control animal and
human gait, biomechanists find that locomotion requires little control if principles of legged …

Recent findings suggest that human cortex is more active during steady-speed unperturbed
locomotion than previously thought. However, techniques that have been used to image the …

Rehabilitation after hemiplegic stroke has typically relied on the training of patients in
compensatory strategies. The translation of neuroscientific research into care has led to new …

In clinical practice, signs of exaggerated tendon tap reflexes associated with muscle
hypertonia are generally thought to be responsible for spastic movement disorders. Most …