Reciprocal interactions between epithelial and mesenchymal tissues play a fundamental
role in the morphogenesis of teeth and regulate all aspects of tooth development. Extensive …

Teeth are found in almost all vertebrates, and they therefore provide a general paradigm for
the study of epithelial organ development and evolution. Here, we review the developmental …

Mesenchymal stem cells (MSCs) are typically defined by their in vitro characteristics, and as
a consequence the in vivo identity of MSCs and their niches are poorly understood. To …

Tissue homeostasis requires the production of newly differentiated cells from resident adult
stem cells. Central to this process is the expansion of undifferentiated intermediates known …

Teeth develop as ectodermal appendages from epithelial and mesenchymal tissues. Tooth
organogenesis is regulated by an intricate network of cell–cell signaling during all steps of …

The continuously growing mouse incisor serves as a valuable model to study stem cell
regulation during organ renewal. Epithelial stem cells are localized in the proximal end of …

Recently, a growing attention has been observed toward potential advantages of stem cell
(SC)-based therapies in regenerative treatments. Mesenchymal stem/stromal cells (MSCs) …

Influenza Virus (IV) pneumonia is associated with severe damage of the lung epithelium and
respiratory failure. Apart from efficient host defense, structural repair of the injured epithelium …

Teeth are unique to vertebrates and have played a central role in their evolution. The
molecular pathways and morphogenetic processes involved in tooth development have …

The mouse incisor is a remarkable tooth that grows throughout the animal's lifetime. This
continuous renewal is fueled by adult epithelial stem cells that give rise to ameloblasts …