The etiology of endemic rickets was discovered a century ago. Vitamin D is the precursor of
25-hydroxyvitamin D and other metabolites, including 1, 25 (OH) 2D, the ligand for the …

1, 25-Dihydroxvitamin D3 [1, 25 (OH) 2D3] is the hormonally active form of vitamin D. The
genomic mechanism of 1, 25 (OH) 2D3 action involves the direct binding of the 1, 25 (OH) …

Background It is unclear whether supplementation with vitamin D reduces the risk of cancer
or cardiovascular disease, and data from randomized trials are limited. Methods We …

Importance Observational studies have reported an association between low serum vitamin
D levels and elevated risk of cardiovascular disease (CVD) events, but such studies cannot …

Low serum concentrations of 25-hydroxyvitamin D (25 [OH] D) have been associated with
many non-skeletal disorders. However, whether low 25 (OH) D is the cause or result of ill …

The aim of this study is to determine the relationships of vitamin D with diabetes, insulin
resistance obesity, and metabolic syndrome. Intra cellular vitamin D receptors and the 1-α …

Background A large number of observational studies have reported harmful effects of low 25-
hydroxyvitamin D (25OHD) levels on non-skeletal outcomes. We performed a systematic …

Vitamin D, the sunshine vitamin, has received a lot of attention recently as a result of a
meteoric rise in the number of publications showing that vitamin D plays a crucial role in a …

This is the fourth edition of the UK National clinical guideline for stroke. It is an integral part
of the broader goal of the Intercollegiate Stroke Working Party to improve the care of people …

Vitamin D is a precursor of the steroid hormone calcitriol that is crucial for bone and mineral
metabolism. Both the high prevalence of vitamin D deficiency in the general population and …