Biogeography is the study of species distribution and diversity within an ecosystem and is at
the core of how we understand ecosystem dynamics and interactions at the macroscale. In …

In this review we discuss mucus, the viscoelastic secretion from goblet or mucous producing
cells that lines the epithelial surfaces of all organs exposed to the external world. Mucus is a …

Mucus is a selective barrier to particles and molecules, preventing penetration to the
epithelial surface of mucosal tissues. Significant advances in transmucosal drug delivery …

Intestinal mucus plays important roles in protecting the epithelial surfaces against
pathogens, supporting the colonization with commensal bacteria, maintaining an …

In this contribution, we review the molecular and physiological barriers to oral delivery of
peptides and nanoparticles. We discuss the opportunities and predictivity of various in vitro …

Mucosal surfaces are a main entry point for pathogens and the principal sites of defense
against infection. Both bacteria and phage are associated with this mucus. Here we show …

Oral delivery is the most common method for drug administration. However, poor solubility,
stability, and bioavailability of many drugs make achieving therapeutic levels via the …

A layer of mucus covers the surface of all wet epithelia throughout the human body. Mucus is
a hydrogel mainly composed of water, mucins (glycoproteins), DNA, proteins, lipids, and cell …

The presence of a mucus layer that covers the surface of a variety of organs has been
capitalized to develop mucoadhesive dosage forms that remain in the administration site for …

Cells release extracellular vesicles (EVs) to communicate over long distances, which
requires EVs to traverse the extracellular matrix (ECM). However, given that the size of EVs …