[HTML][HTML] Horizontal gene transfer: from evolutionary flexibility to disease progression

M Emamalipour, K Seidi, S Zununi Vahed… - Frontiers in cell and …, 2020 - frontiersin.org
Flexibility in the exchange of genetic material takes place between different organisms of the
same or different species. This phenomenon is known to play a key role in the genetic …

Class 1 integrons as invasive species

MR Gillings - Current opinion in microbiology, 2017 - Elsevier
Highlights•Clinical class 1 integrons are descended from a single, recent ancestor.•They
have rapidly spread between diverse bacteria, vertebrate hosts and countries.•This spread …

Lateral gene transfer, bacterial genome evolution, and the Anthropocene

MR Gillings - Annals of the New York Academy of Sciences, 2017 - Wiley Online Library
Lateral gene transfer (LGT) has significantly influenced bacterial evolution since the origins
of life. It helped bacteria generate flexible, mosaic genomes and enables individual cells to …

Integron activity accelerates the evolution of antibiotic resistance

C Souque, JA Escudero, RC MacLean - Elife, 2021 - elifesciences.org
Mobile integrons are widespread genetic platforms that allow bacteria to modulate the
expression of antibiotic resistance cassettes by shuffling their position from a common …

Polycyclic aromatic hydrocarbons (PAHs) enriching antibiotic resistance genes (ARGs) in the soils

B Chen, R He, K Yuan, E Chen, L Lin, X Chen… - Environmental …, 2017 - Elsevier
The prevalence of antibiotic resistance genes (ARGs) in modern environment raises an
emerging global health concern. In this study, soil samples were collected from three sites in …

On the contribution of reclaimed wastewater irrigation to the potential exposure of humans to antibiotics, antibiotic resistant bacteria and antibiotic resistance genes …

B Piña, JM Bayona, A Christou… - Journal of …, 2020 - Elsevier
Antibiotic resistance (AR) is becoming a worldwide threat due to the increasing occurrence
of antibiotic-resistant pathogenic bacterial strains. There is a general consensus about the …

CRISPR-Cas system as a promising player against bacterial infection and antibiotic resistance

M Abavisani, R Khayami, M Hoseinzadeh… - Drug Resistance …, 2023 - Elsevier
The phenomenon of antibiotic resistance (AR) and its increasing global trends and
destructive waves concerns patients and the healthcare system. In order to combat AR, it is …

The application of the CRISPR-Cas system in antibiotic resistance

S Tao, H Chen, N Li, W Liang - Infection and drug resistance, 2022 - Taylor & Francis
The emergence and global epidemic of antimicrobial resistance (AMR) poses a serious
threat to global public health in recent years. AMR genes are shared between bacterial …

[HTML][HTML] Estuarine sediments are key hotspots of intracellular and extracellular antibiotic resistance genes: A high-throughput analysis in Haihe Estuary in China

Z Zhao, K Zhang, N Wu, W Li, W Xu, Y Zhang… - Environment …, 2020 - Elsevier
Estuaries lie between terrestrial/freshwater and marine ecosystems, receive considerable
pollutant input from land-based sources, and are considerably influenced by human …

PAHs accelerate the propagation of antibiotic resistance genes in coastal water microbial community

J Wang, Z Zhao, J Chen, H Lu, G Liu, J Zhou… - Environmental …, 2017 - Elsevier
Antibiotic resistance genes (ARGs) have been regarded as emerging contaminants and
have attracted growing attention owing to their widespread presence in the environment. In …