Peptidomics and proteogenomics: background, challenges and future needs
R Vitorino, M Choudhury, S Guedes… - Expert Review of …, 2021 - Taylor & Francis
Introduction With available genomic data and related information, it is becoming possible to
better highlight mutations or genomic alterations associated with a particular disease or …
better highlight mutations or genomic alterations associated with a particular disease or …
[HTML][HTML] Improved identification of small open reading frames encoded peptides by top-down proteomic approaches and de novo sequencing
B Wang, Z Wang, N Pan, J Huang, C Wan - International Journal of …, 2021 - mdpi.com
Small open reading frames (sORFs) have translational potential to produce peptides that
play essential roles in various biological processes. Nevertheless, many sORF-encoded …
play essential roles in various biological processes. Nevertheless, many sORF-encoded …
Updates on resources, software tools, and databases for plant proteomics in 2016–2017
BB Misra - Electrophoresis, 2018 - Wiley Online Library
Proteomics data processing, annotation, and analysis can often lead to major hurdles in
large‐scale high‐throughput bottom‐up proteomics experiments. Given the recent rise in …
large‐scale high‐throughput bottom‐up proteomics experiments. Given the recent rise in …
Systematic Identification of Microproteins during the Development of Drosophila melanogaster
Z Wang, N Pan, J Yan, J Wan… - Journal of Proteome …, 2022 - ACS Publications
Short open reading frame-encoded peptides (SEPs) are microproteins with less than 100
amino acids that play an essential role in the growth and development of organisms. There …
amino acids that play an essential role in the growth and development of organisms. There …
[HTML][HTML] Mapping microproteins and ncRNA-encoded polypeptides in different mouse tissues
N Pan, Z Wang, B Wang, J Wan, C Wan - Frontiers in Cell and …, 2021 - frontiersin.org
Small open reading frame encoded peptides (SEPs), also called microproteins, play a vital
role in biological processes. Plenty of their open reading frames are located within the non …
role in biological processes. Plenty of their open reading frames are located within the non …
[HTML][HTML] Fast, quantitative and variant enabled mapping of peptides to genomes
Current tools for visualization and integration of proteomics with other omics datasets are
inadequate for large-scale studies and capture only basic sequence identity information …
inadequate for large-scale studies and capture only basic sequence identity information …
Proteogenomics 101: a primer on database search strategies
Proteogenomics refers to the integration of high-throughput genomics/transcriptomics with
proteomics data for genome annotation, novel gene discovery, and variant peptide detection …
proteomics data for genome annotation, novel gene discovery, and variant peptide detection …
[HTML][HTML] Females translate male mRNA transferred during mating
LM Matzkin, JM Bono, HK Pigage, CW Allan, F Diaz… - bioRxiv, 2023 - ncbi.nlm.nih.gov
Although RNA is found in the seminal fluid of diverse organisms, it is unknown whether this
RNA is functional within females. Here, we develop an experimental proteomic method …
RNA is functional within females. Here, we develop an experimental proteomic method …
[HTML][HTML] Proteogenomic analysis of breast cancer transcriptomic and proteomic data, using de novo transcript assembly: genome-wide identification of novel peptides …
PS Hari, L Balakrishnan, C Kotyada, AE John… - Molecular & Cellular …, 2022 - ASBMB
We have carried out proteogenomic analysis of the breast cancer transcriptomic and
proteomic data, available at The Clinical Proteomic Tumor Analysis Consortium resource, to …
proteomic data, available at The Clinical Proteomic Tumor Analysis Consortium resource, to …
MutCombinator: identification of mutated peptides allowing combinatorial mutations using nucleotide-based graph search
Motivation Proteogenomics has proven its utility by integrating genomics and proteomics.
Typical approaches use data from next-generation sequencing to infer proteins expressed …
Typical approaches use data from next-generation sequencing to infer proteins expressed …