Practical aspects of microRNA target prediction
T M. Witkos, E Koscianska… - Current molecular …, 2011 - benthamdirect.com
microRNAs (miRNAs) are endogenous non-coding RNAs that control gene expression at
the posttranscriptional level. These small regulatory molecules play a key role in the majority …
the posttranscriptional level. These small regulatory molecules play a key role in the majority …
Differential expression of microRNAs in Alzheimer's disease brain, blood, and cerebrospinal fluid
P Takousis, A Sadlon, J Schulz, I Wohlers… - Alzheimer's & …, 2019 - Elsevier
Abstract Introduction Several microRNAs (miRNAs) have been implicated in Alzheimer's
disease pathogenesis, but the evidence from individual case-control studies remains …
disease pathogenesis, but the evidence from individual case-control studies remains …
Exosomal cell-to-cell transmission of alpha synuclein oligomers
Background Aggregation of alpha-synuclein (αsyn) and resulting cytotoxicity is a hallmark of
sporadic and familial Parkinson's disease (PD) as well as dementia with Lewy bodies, with …
sporadic and familial Parkinson's disease (PD) as well as dementia with Lewy bodies, with …
[HTML][HTML] Identification of blood microRNAs associated to Parkinsońs disease
R Margis, R Margis, CRM Rieder - Journal of biotechnology, 2011 - Elsevier
The present study demonstrates that blood samples can be used as a source of miRNA
identification associated to Parkinson's disease (PD). A set of six differentially expressed …
identification associated to Parkinson's disease (PD). A set of six differentially expressed …
microRNA-based biomarkers in Alzheimer's disease (AD)
Y Zhao, V Jaber, PN Alexandrov, A Vergallo… - Frontiers in …, 2020 - frontiersin.org
Alzheimer's disease (AD) is a multifactorial, age-related neurological disease characterized
by complex pathophysiological dynamics taking place at multiple biological levels, including …
by complex pathophysiological dynamics taking place at multiple biological levels, including …
Moringa oleifera: A Tree of Life as a Promising Medicinal Plant for Neurodegenerative Diseases
S Ghimire, L Subedi, N Acharya… - Journal of agricultural …, 2021 - ACS Publications
Moringa oleifera, popularly known as a miracle tree or tree of life, has been extensively used
as a functional food and nutritional asset worldwide. Ethnomedicinal and traditional uses of …
as a functional food and nutritional asset worldwide. Ethnomedicinal and traditional uses of …
Impaired neurosteroid synthesis in multiple sclerosis
F Noorbakhsh, KK Ellestad, F Maingat, KG Warren… - Brain, 2011 - academic.oup.com
High-throughput technologies have led to advances in the recognition of disease pathways
and their underlying mechanisms. To investigate the impact of micro-RNAs on the disease …
and their underlying mechanisms. To investigate the impact of micro-RNAs on the disease …
[HTML][HTML] Engineered smart materials for RNA based molecular therapy to treat Glioblastoma
Glioblastoma (GBM) is an aggressive malignancy of the central nervous system (CNS) that
remains incurable despite the multitude of improvements in cancer therapeutics. The …
remains incurable despite the multitude of improvements in cancer therapeutics. The …
Viral delivery of miR-196a ameliorates the SBMA phenotype via the silencing of CELF2
Y Miyazaki, H Adachi, M Katsuno, M Minamiyama… - Nature medicine, 2012 - nature.com
Spinal and bulbar muscular atrophy (SBMA) is an inherited neurodegenerative disorder
caused by the expansion of the polyglutamine (polyQ) tract of the androgen receptor (AR …
caused by the expansion of the polyglutamine (polyQ) tract of the androgen receptor (AR …
Brain-specific knockdown of miR-29 results in neuronal cell death and ataxia in mice
R Roshan, S Shridhar, MA Sarangdhar, A Banik… - Rna, 2014 - rnajournal.cshlp.org
Several microRNAs have been implicated in neurogenesis, neuronal differentiation,
neurodevelopment, and memory. Development of miRNA-based therapeutics, however …
neurodevelopment, and memory. Development of miRNA-based therapeutics, however …