Polymeric delivery of therapeutic nucleic acids

R Kumar, CF Santa Chalarca, MR Bockman… - Chemical …, 2021 - ACS Publications
The advent of genome editing has transformed the therapeutic landscape for several
debilitating diseases, and the clinical outlook for gene therapeutics has never been more …

Zwitterionic materials for antifouling membrane surface construction

M He, K Gao, L Zhou, Z Jiao, M Wu, J Cao, X You… - Acta biomaterialia, 2016 - Elsevier
Membrane separation processes are often perplexed by severe and ubiquitous membrane
fouling. Zwitterionic materials, keeping electric neutrality with equivalent positive and …

Zwitterionic nanohydrogel grafted PVDF membranes with comprehensive antifouling property and superior cycle stability for oil‐in‐water emulsion separation

Y Zhu, J Wang, F Zhang, S Gao, A Wang… - Advanced Functional …, 2018 - Wiley Online Library
Fouling caused by oil and other pollutants is one of the most serious challenges for
membranes used for oil/water separation. Aiming at improving the comprehensive …

Surface modification and endothelialization of biomaterials as potential scaffolds for vascular tissue engineering applications

X Ren, Y Feng, J Guo, H Wang, Q Li, J Yang… - Chemical Society …, 2015 - pubs.rsc.org
Surface modification and endothelialization of vascular biomaterials are common
approaches that are used to both resist the nonspecific adhesion of proteins and improve …

The blood compatibility challenge. Part 2: Protein adsorption phenomena governing blood reactivity

JL Brash, TA Horbett, RA Latour, P Tengvall - Acta biomaterialia, 2019 - Elsevier
The adsorption of proteins is the initiating event in the processes occurring when blood
contacts a “foreign” surface in a medical device, leading inevitably to thrombus formation …

Applications of zwitterionic polymers

L Zheng, HS Sundaram, Z Wei, C Li, Z Yuan - Reactive and Functional …, 2017 - Elsevier
Zwitterionic polymers are characterized with equal anion and cation groups on the
molecular chains, which make them highly hydrophilic and antifouling. They can resist …

Superhydrophilic in-situ-cross-linked zwitterionic polyelectrolyte/PVDF-blend membrane for highly efficient oil/water emulsion separation

Y Zhu, W Xie, F Zhang, T Xing, J Jin - ACS applied materials & …, 2017 - ACS Publications
Because of weak hydrophilicity, membranes always experience fouling problems during
separations. This phenomenon seriously impedes the development of membrane …

Blood compatible materials: state of the art

X Liu, L Yuan, D Li, Z Tang, Y Wang, G Chen… - Journal of Materials …, 2014 - pubs.rsc.org
Devices that function in contact with blood are ubiquitous in clinical medicine and
biotechnology. These devices include vascular grafts, coronary stents, heart valves …

Hemocompatibility challenge of membrane oxygenator for artificial lung technology

BPN Thi, BTD Nguyen, IS Jeong, JF Kim - Acta Biomaterialia, 2022 - Elsevier
The artificial lung (AL) technology is one of the membrane-based artificial organs that partly
augments lung functions, ie blood oxygenation and CO 2 removal. It is generally employed …

Advanced zwitterionic polymeric membranes for diverse applications beyond antifouling

G Gu, X Yang, Y Li, J Guo, J Huang… - Separation and …, 2024 - Elsevier
Zwitterionic polymers, characterized by their possession of both cationic and anionic groups,
are overall electrically neutral and capable of forming hydration layers on surfaces through …