SARS-CoV-2 infection of the liver directly contributes to hepatic impairment in patients with COVID-19

Y Wang, S Liu, H Liu, W Li, F Lin, L Jiang, X Li, P Xu… - Journal of …, 2020 - Elsevier
Background & Aims Liver enzyme abnormalities are common in patients with coronavirus
disease 2019 (COVID-19). Whether or not severe acute respiratory syndrome coronavirus 2 …

Cancer biology as revealed by the research autopsy

CA Iacobuzio-Donahue, C Michael, P Baez… - Nature reviews …, 2019 - nature.com
A research autopsy is a post-mortem medical procedure performed on a deceased
individual with the primary goal of collecting tissue to support basic and translational …

An interdisciplinary review of the thanatomicrobiome in human decomposition

GT Javan, SJ Finley, S Tuomisto, A Hall… - … Science, Medicine and …, 2019 - Springer
Death does not occur instantaneously and organs do not decompose at the same rate or in
the same way. Nulligravid human uteri and prostate glands are the last internal organs to …

Analysis of donor pancreata defines the transcriptomic signature and microenvironment of early neoplastic lesions

ES Carpenter, AM Elhossiny, P Kadiyala, J Li, J McGue… - Cancer Discovery, 2023 - AACR
The adult healthy human pancreas has been poorly studied given the lack of indication to
obtain tissue from the pancreas in the absence of disease and rapid postmortem …

[HTML][HTML] Virtual histological staining of unlabeled autopsy tissue

Y Li, N Pillar, J Li, T Liu, D Wu, S Sun, G Ma… - Nature …, 2024 - nature.com
Traditional histochemical staining of post-mortem samples often confronts inferior staining
quality due to autolysis caused by delayed fixation of cadaver tissue, and such chemical …

[HTML][HTML] Postmortem protein degradation as a tool to estimate the PMI: A systematic review

A Zissler, W Stoiber, P Steinbacher, J Geissenberger… - Diagnostics, 2020 - mdpi.com
Objectives: We provide a systematic review of the literature to evaluate the current research
status of protein degradation-based postmortem interval (PMI) estimation. Special attention …

The use of cardiac troponin T (cTnT) in the postmortem diagnosis of acute myocardial infarction and sudden cardiac death: A systematic review

C Barberi, KE van den Hondel - Forensic science international, 2018 - Elsevier
Being sudden cardiac death (SCD) and acute myocardial infarction (AMI) frequent
occurrences in forensic medicine, extensive research has been published about the use of …

[HTML][HTML] Diagnostic roles of postmortem cTn I and cTn T in cardiac death with special regard to myocardial infarction: a systematic literature review and meta-analysis

Z Cao, M Zhao, C Xu, T Zhang, Y Jia, T Wang… - International journal of …, 2019 - mdpi.com
Background: Cardiac troponin I (cTn I) and cardiac troponin T (cTn T) are currently widely
used as diagnostic biomarkers for myocardial injury caused by ischemic heart diseases in …

[HTML][HTML] Histologic and Quality Assessment of Genotype-Tissue Expression (GTEx) Research Samples: A Large Postmortem Tissue Collection

L Sobin, M Barcus, PA Branton… - … of Pathology & …, 2024 - meridian.allenpress.com
Context.—The National Institutes of Health Genotype-Tissue Expression (GTEx) project was
developed to elucidate how genetic variation influences gene expression in multiple normal …

Analysis of the persistence time of the SARS-CoV-2 virus in the cadaver and the risk of passing infection to autopsy staff

I Aquila, P Ricci, CF Bonetta, MA Sacco… - Medico-Legal …, 2021 - journals.sagepub.com
The activity of the SARS-CoV-2 virus has not yet been studied in a post-mortem setting. The
absence of these data has led to the prohibition of exposure of infected corpses during …