Frailty in older people living with HIV: current status and clinical management

DS Kehler, J Milic, G Guaraldi, T Fulop, J Falutz - BMC geriatrics, 2022 - Springer
This paper will update care providers on the clinical and scientific aspects of frailty which
affects an increasing proportion of older people living with HIV (PLWH). The successful use …

To be frail or not to be frail: this is the question—a critical narrative review of frailty

S Sciacchitano, V Carola, G Nicolais… - Journal of Clinical …, 2024 - mdpi.com
Many factors have contributed to rendering frailty an emerging, relevant, and very popular
concept. First, many pandemics that have affected humanity in history, including COVID-19 …

Increasing prevalence of frailty and its association with readmission and mortality among hospitalized patients with IBD

AS Faye, T Wen, A Soroush… - Digestive diseases and …, 2021 - Springer
Background Although age is often used as a clinical risk stratification tool, recent data have
suggested that adverse outcomes are driven by frailty rather than chronological age. Aims In …

Transplant centers that assess frailty as part of clinical practice have better outcomes

X Chen, Y Liu, V Thompson, NM Chu, EA King… - BMC geriatrics, 2022 - Springer
Background Frailty predicts adverse post-kidney transplant (KT) outcomes, yet the impact of
frailty assessment on center-level outcomes remains unclear. We sought to test whether …

Frailty in people living with HIV

M Bloch - AIDS research and therapy, 2018 - Springer
The life expectancy of people living with HIV (PLHIV) has dramatically improved with
effective and well-tolerated antiretroviral therapy. This presents a new challenge in caring for …

Frailty assessment as part of transplant listing: yes, no or maybe?

MA McAdams-DeMarco, AK Thind… - Clinical Kidney …, 2023 - academic.oup.com
Frailty, characterized by a decreased physiological reserve and an increased vulnerability to
stressors, is common among kidney transplant (KT) candidates and recipients. In this review …

Eight-year changes in multimorbidity and frailty in adults with type 2 diabetes mellitus: associations with cognitive and physical function and mortality

MA Espeland, JN Justice, J Bahnson… - The Journals of …, 2022 - academic.oup.com
Background Indices of multimorbidity and deficit accumulation (ie, frailty indices) have been
proposed as markers of biological aging. If true, changes in these indices over time should …

Frailty in people living with HIV

J Falutz - Current HIV/AIDS Reports, 2020 - Springer
Abstract Purpose of Review Different factors contribute to the decreased overall long-term
survival in treated people living with HIV (PLWH). This paper will review the state of physical …

The dynamic association between Frailty, CD4 and CD4/CD8 ratio in people aging with HIV

G Guaraldi, S Zona, AR Silva, M Menozzi, G Dolci… - PloS one, 2019 - journals.plos.org
Objective To investigate the association between current CD4+ T-cell count and CD4/CD8+
ratio with severity of frailty among people aging with HIV. Methods Cross-sectional …

Frailty is associated with the clinical expression of neuropsychological deficits in older adults

M Canevelli, LMK Wallace, G Bruno… - European Journal of …, 2024 - Wiley Online Library
Background and purpose The aim was to determine whether frailty is associated with the
relationship between neuropsychological markers and global cognition in older adults …