TGF-β1 signalling in Alzheimer's pathology and cytoskeletal reorganization: a specialized Tau perspective
M Kapoor, S Chinnathambi - Journal of Neuroinflammation, 2023 - Springer
Microtubule-associated protein, Tau has been implicated in Alzheimer's disease for its
detachment from microtubules and formation of insoluble intracellular aggregates within the …
detachment from microtubules and formation of insoluble intracellular aggregates within the …
Vitamin D in neurological diseases
Vitamin D may have multiple effects on the nervous system and its deficiency can represent
a possible risk factor for the development of many neurological diseases. Recent studies are …
a possible risk factor for the development of many neurological diseases. Recent studies are …
Cerebrospinal fluid p-tau217 performs better than p-tau181 as a biomarker of Alzheimer's disease
S Janelidze, E Stomrud, R Smith, S Palmqvist… - Nature …, 2020 - nature.com
Cerebrospinal fluid (CSF) p-tau181 (tau phosphorylated at threonine 181) is an established
biomarker of Alzheimer's disease (AD), reflecting abnormal tau metabolism in the brain …
biomarker of Alzheimer's disease (AD), reflecting abnormal tau metabolism in the brain …
[HTML][HTML] X-linked ubiquitin-specific peptidase 11 increases tauopathy vulnerability in women
Although women experience significantly higher tau burden and increased risk for
Alzheimer's disease (AD) than men, the underlying mechanism for this vulnerability has not …
Alzheimer's disease (AD) than men, the underlying mechanism for this vulnerability has not …
Advances of zebrafish in neurodegenerative disease: from models to drug discovery
X Wang, JB Zhang, KJ He, F Wang… - Frontiers in Pharmacology, 2021 - frontiersin.org
Neurodegenerative disease (NDD), including Alzheimer's disease, Parkinson's disease, and
amyotrophic lateral sclerosis, are characterized by the progressive loss of neurons which …
amyotrophic lateral sclerosis, are characterized by the progressive loss of neurons which …
Brahmi (Bacopa monnieri): An ayurvedic herb against the Alzheimer's disease
T Dubey, S Chinnathambi - Archives of biochemistry and biophysics, 2019 - Elsevier
Ayurveda is the medicinal science, dealing with utilization of naturally available plant
products for treatment. A wide variety of neuroprotective herbs have been reported in …
products for treatment. A wide variety of neuroprotective herbs have been reported in …
Phagocytosis of full-length Tau oligomers by Actin-remodeling of activated microglia
Background Alzheimer's disease is associated with the accumulation of intracellular Tau
tangles within neurons and extracellular amyloid-β plaques in the brain parenchyma, which …
tangles within neurons and extracellular amyloid-β plaques in the brain parenchyma, which …
Role of tau in various tauopathies, treatment approaches, and emerging role of nanotechnology in neurodegenerative disorders
A few protein kinases and phosphatases regulate tau protein phosphorylation and an
imbalance in their enzyme activity results in tau hyper-phosphorylation. Aberrant tau …
imbalance in their enzyme activity results in tau hyper-phosphorylation. Aberrant tau …
Insulin resistance at the crossroad of Alzheimer disease pathology: A review
J Berlanga-Acosta, G Guillén-Nieto… - Frontiers in …, 2020 - frontiersin.org
Insulin plays a major neuroprotective and trophic function for cerebral cell population, thus
countering apoptosis, beta-amyloid toxicity, and oxidative stress; favoring neuronal survival; …
countering apoptosis, beta-amyloid toxicity, and oxidative stress; favoring neuronal survival; …
Role of dietary fatty acids in microglial polarization in Alzheimer's disease
SE Desale, S Chinnathambi - Journal of neuroinflammation, 2020 - Springer
Microglial polarization is an utmost important phenomenon in Alzheimer's disease that
influences the brain environment. Polarization depends upon the types of responses that …
influences the brain environment. Polarization depends upon the types of responses that …