Various internal and external factors negatively affect the homeostatic equilibrium of
organisms at the molecular to the whole-body level, inducing the so-called state of stress …

Ferroptosis is a novel regulated cell death pattern discovered when studying the mechanism
of erastin-killing RAS mutant tumor cells in 2012. It is an iron-dependent programmed cell …

Both type 1 and type 2 diabetes adversely affect the microvasculature in multiple organs.
Our understanding of the genesis of this injury and of potential interventions to prevent, limit …

Diabetes prevalence is increasing worldwide, especially through the increase of type 2
diabetes. Diabetic nephropathy occurs in up to 40% of diabetic patients and is the leading …

Chronic kidney disease (CKD) is a common and serious problem that adversely affects
human health, limits longevity and increases costs to health‐care systems worldwide. Its …

The precorneal tear film is a complex mixture of proteins, lipids, metabolites, and electrolytes
with different structures and functionalities. Sustainable production of each tear component …

Chronic kidney disease (CKD) is a major public health problem. The classification of CKD by
KDOQI and KDIGO and the routine eGFR reporting have resulted in increased identification …

Purpose of review: Diabetic nephropathy (DN) is a progressive kidney disease caused by
alterations in kidney architecture and function, and constitutes one of the leading causes of …

Since the beginning of the 1990's diverse types of metabolites originating from
polyunsaturated fatty acids, formed under autooxidative conditions were discovered. Known …

Oxidative stress plays a major role in diabetes as well as in Alzheimer's disease and other
related neurological diseases. Intracellular oxidative stress arises due to the imbalance in …