16th international congress on antiphospholipid antibodies task force report on antiphospholipid syndrome treatment trends

H Cohen, MJ Cuadrado, D Erkan, A Duarte-Garcia… - Lupus, 2020 - journals.sagepub.com
Antiphospholipid syndrome (APS), an acquired autoimmune thrombophilia, is characterised
by thrombosis and/or pregnancy morbidity in association with persistent antiphospholipid …

[HTML][HTML] The role of beta-2-glycoprotein I in health and disease associating structure with function: More than just APS

T McDonnell, C Wincup, I Buchholz, C Pericleous… - Blood reviews, 2020 - Elsevier
Abstract Beta-2-Glycoprotein I (β2GPI) plays a number of essential roles throughout the
body. β2GPI, C-reactive protein and thrombomodulin are the only three proteins that …

14th international congress on antiphospholipid antibodies task force report on antiphospholipid syndrome treatment trends

D Erkan, CL Aguiar, D Andrade, H Cohen… - Autoimmunity …, 2014 - Elsevier
Antiphospholipid Syndrome (APS) is characterized by vascular thrombosis and/or
pregnancy morbidity occurring in patients with persistent antiphospholipid antibodies (aPL) …

Obstetric and vascular antiphospholipid syndrome: same antibodies but different diseases?

PL Meroni, MO Borghi, C Grossi… - Nature Reviews …, 2018 - nature.com
Recurrent thrombosis and miscarriages are the main clinical manifestations of
antiphospholipid syndrome (APS). Although most patients display both clinical signs, some …

Pathogenesis and management of antiphospholipid syndrome

DRJ Arachchillage, M Laffan - British journal of haematology, 2017 - Wiley Online Library
Antiphospholipid antibodies are a heterogeneous group of autoantibodies that have clear
associations with thrombosis and pregnancy morbidity, and which together constitute the …

The significance of autoantibodies against β2-glycoprotein I

PG de Groot, RT Urbanus - Blood, The Journal of the American …, 2012 - ashpublications.org
The antiphospholipid syndrome (APS) is defined by the persistent presence of
antiphospholipid antibodies in patients with a history of thrombosis and/or pregnancy …

A non–complement-fixing antibody to β2 glycoprotein I as a novel therapy for antiphospholipid syndrome

C Agostinis, P Durigutto, D Sblattero… - Blood, The Journal …, 2014 - ashpublications.org
A single-chain fragment variable (scFv) recognizing β2-glycoprotein 1 (β2GPI) from humans
and other species was isolated from a human phage display library and engineered to …

[HTML][HTML] Antiphospholipid syndrome and pregnancy: pathogenesis to translation

VM Abrahams, LW Chamley… - Arthritis & rheumatology …, 2017 - ncbi.nlm.nih.gov
The antiphospholipid syndrome (APS) is an autoimmune condition associated with
thrombosis (venous or arterial) and adverse pregnancy outcomes. Investigation of APS …

Beta 2 glycoprotein I and neutrophil extracellular traps: potential bridge between innate and adaptive immunity in anti-phospholipid syndrome

C Grossi, N Capitani, M Benagiano, CT Baldari… - Frontiers in …, 2023 - frontiersin.org
Antiphospholipid syndrome (APS) is a systemic autoimmune disorder characterized by
recurrent vascular thrombosis and miscarriages in the absence of known causes. Antibodies …

The pathogenic role of autoantibodies in recurrent pregnancy loss

S D'Ippolito, C Ticconi, C Tersigni… - American Journal of …, 2020 - Wiley Online Library
In the present manuscript, we review the recent research investigating the pathogenic
association between most studied autoantibodies and recurrent pregnancy loss. Pregnancy …