Increased epithelial permeability is a common and important consequence of mucosal
inflammation that results in perturbed body homeostasis and enhanced exposure to external …

The intestinal epithelial cells (IECs) form a selective permeability barrier separating luminal
content from underlying tissues. Upon injury, the intestinal epithelium undergoes a wound …

Epithelial tissues are defined by polarized epithelial cells that are integrated into tissues and
exhibit barrier function in order to regulate what is allowed to pass between cells. Cell-cell …

In this study we sought to identify how contractility at adherens junctions influences apoptotic
cell extrusion. We first found that the generation of effective contractility at steady-state …

Adherens junctions (AJs) are evolutionarily conserved plasma-membrane structures that
mediate cell–cell adhesions in multicellular organisms. They are organized by several types …

ABSTRACT Human MCF-7/6 breast cancer cells differ from their MCF-7/AZ counterparts by
their invasiveness in a number of assays in vitro, such as invasion of MCF-7 spheroids into …

The actin cytoskeleton is a critical regulator of intestinal mucosal barrier permeability, and
the integrity of epithelial adherens junctions (AJ) and tight junctions (TJ). Non muscle myosin …

Ablation of nonmuscle myosin (NM) II-A or NM II-B results in mouse embryonic lethality.
Here, we report the results of ablating NM II-C as well as NM II-C/II-B together in mice. NM II …

Background and purpose: Blebbistatin, an inhibitor of myosin‐II‐specific ATPase, has been
used to inhibit contraction of invertebrate and mammalian muscle preparations containing …

Nonmuscle myosin IIA (myosin IIA) is a force-producing protein involved in the process of
cell migration. Its expression has been considered as a bad prognostic indicator in stage I …