[HTML][HTML] Negative effects of a high-fat diet on intestinal permeability: a review

MW Rohr, CA Narasimhulu, TA Rudeski-Rohr… - Advances in …, 2020 - Elsevier
The intestinal tract is the largest barrier between a person and the environment. In this role,
the intestinal tract is responsible not only for absorbing essential dietary nutrients, but also …

Bench to bedside—new insights into the pathogenesis of necrotizing enterocolitis

DJ Hackam, CP Sodhi - Nature reviews Gastroenterology & hepatology, 2022 - nature.com
Necrotizing enterocolitis (NEC) is the leading cause of death and disability from
gastrointestinal disease in premature infants. Recent discoveries have shed light on a …

Diagnosis of neonatal sepsis: the past, present and future

IH Celik, M Hanna, FE Canpolat, M Pammi - Pediatric research, 2022 - nature.com
Sepsis remains a significant cause of neonatal mortality and morbidity, especially in low-and
middle-income countries. Neonatal sepsis presents with nonspecific signs and symptoms …

Necrotizing enterocolitis: new insights into pathogenesis and mechanisms

DF Niño, CP Sodhi, DJ Hackam - Nature reviews Gastroenterology & …, 2016 - nature.com
Necrotizing enterocolitis (NEC) is the most frequent and lethal disease of the gastrointestinal
tract of preterm infants. At present, NEC is thought to develop in the premature host in the …

The intestinal microbiome in early life: health and disease

MC Arrieta, LT Stiemsma, N Amenyogbe… - Frontiers in …, 2014 - frontiersin.org
Human microbial colonization begins at birth and continues to develop and modulate in
species abundance for about 3 years, until the microbiota becomes adult-like. During the …

Lipopolysaccharide regulation of intestinal tight junction permeability is mediated by TLR4 signal transduction pathway activation of FAK and MyD88

S Guo, M Nighot, R Al-Sadi, T Alhmoud… - The Journal of …, 2015 - journals.aai.org
Gut-derived bacterial LPS plays an essential role in inducing intestinal and systemic
inflammatory responses and have been implicated as a pathogenic factor in necrotizing …

Necrotizing enterocolitis

J Neu, WA Walker - New England Journal of Medicine, 2011 - Mass Medical Soc
Necrotizing Enterocolitis | New England Journal of Medicine Skip to main content Access
provided byUT MD ANDERSON CANCER CENTER The New England Journal of Medicine …

Necrotizing enterocolitis: It's not all in the gut

AL Meister, KK Doheny… - Experimental biology and …, 2020 - journals.sagepub.com
Necrotizing enterocolitis is the leading cause of death due to gastrointestinal disease in
preterm neonates, affecting 5–12% of neonates born at a very-low birth weight. Necrotizing …

Toll-like receptor signalling in the intestinal epithelium: how bacterial recognition shapes intestinal function

MT Abreu - Nature reviews immunology, 2010 - nature.com
A single layer of epithelial cells lines the small and large intestines and functions as a barrier
between commensal bacteria and the rest of the body. Ligation of Toll-like receptors (TLRs) …

The human milk oligosaccharides 2'-fucosyllactose and 6'-sialyllactose protect against the development of necrotizing enterocolitis by inhibiting toll-like receptor 4 …

CP Sodhi, P Wipf, Y Yamaguchi, WB Fulton… - Pediatric …, 2021 - nature.com
Background Necrotizing enterocolitis (NEC) develops through exaggerated toll-like receptor
4 (TLR4) signaling in the intestinal epithelium. Breast milk is rich in non-digestible …