Biological challenges and technological opportunities for respiratory syncytial virus vaccine development

BS Graham - Immunological reviews, 2011 - Wiley Online Library
Respiratory syncytial virus (RSV) is an important cause of respiratory disease causing high
rates of hospitalizations in infants, significant morbidity in children and adults, and excess …

Current animal models for understanding the pathology caused by the respiratory syncytial virus

MJ Altamirano-Lagos, FE Díaz, MA Mansilla… - Frontiers in …, 2019 - frontiersin.org
The human respiratory syncytial virus (hRSV) is the main etiologic agent of severe lower
respiratory tract infections that affect young children throughout the world, associated with …

Prenatal nicotine exposure blunts the cardiorespiratory response to hypoxia in lambs

O Hafström, J Milerad, HW Sundell - American journal of …, 2002 - atsjournals.org
Because smoking during pregnancy is a major risk factor for late fetal death and the sudden
infant death syndrome, we investigated cardiorespiratory defense mechanisms to hypoxia in …

Apparent life-threatening event: a review

CC DeWolfe - Pediatric Clinics, 2005 - pediatric.theclinics.com
The term ''apparent life-threatening event''(ALTE) refers to a complex of symptoms that
presents unexpectedly in an infant and is of concern to the caregiver and often cannot be …

Review of risk factors for sudden infant death syndrome.

FM Sullivan, SM Barlow - Paediatric and perinatal epidemiology, 2001 - europepmc.org
Sudden infant death syndrome (SIDS) accounts for the largest number of deaths during the
first year of life in developed countries. The possible causes of SIDS are numerous and, to …

Upper airway reflexes in response to gastric reflux

JP Praud - Paediatric respiratory reviews, 2010 - Elsevier
Gastric reflux, and especially laryngopharyngeal reflux, occur several times a day in every
infant. Most often, this does not pose any problem. However, in certain conditions, the …

Consequences of immature and senescent immune responses for infection with respiratory syncytial virus

AMW Malloy, AR Falsey, TJ Ruckwardt - Challenges and opportunities for …, 2013 - Springer
Infants in the first 6 months of life and older adults (> 65 years of age) are disproportionately
burdened with respiratory syncytial virus (RSV)-associated morbidity and mortality. While …

Arousal from sleep mechanisms in infants

P Franco, I Kato, HL Richardson, JSC Yang… - Sleep Medicine, 2010 - Elsevier
Arousals from sleep allow sleep to continue in the face of stimuli that normally elicit
responses during wakefulness and also permit awakening to the most urgent information …

[HTML][HTML] Reduced clearance of respiratory syncytial virus infection in a preterm lamb model

DK Meyerholz, B Grubor, SJ Fach, RE Sacco… - Microbes and …, 2004 - Elsevier
Respiratory syncytial virus (RSV) causes significant respiratory disease in children
worldwide. For the study of severe RSV disease seen in preterm infants, a suitable animal …

Laryngeal sensitivity in the neonatal period: from bench to bedside

P Reix, M St‐Hilaire, JP Praud - Pediatric pulmonology, 2007 - Wiley Online Library
Laryngeal sensitivity in the newborn has been a subject of great interest for both researchers
and clinicians for a number of years. From a clinical standpoint, laryngeal sensitivity is …