The prefrontal cortex (PFC) is not only important in executive functions, but also pain
processing. The latter is dependent on its connections to other areas of the cerebral …

Fibromyalgia (FM) is a common chronic pain disorder that presents diagnostic challenges
for clinicians. Several classification, diagnostic and screening criteria have been developed …

Chronic pain is one of the most prevalent health problems in our modern world, with millions
of people debilitated by conditions such as back pain, headache and arthritis. To address …

Objective Emotion regulation (ER) includes a set of cognitive and attentional processes
used to change or maintain emotional state. A small but growing body of research suggests …

This article provides a neurobiological account of symptoms that have been called
'hysterical','psychogenic'or 'medically unexplained', which we will call functional motor and …

Pain is a subjective sensory experience that can, mostly, be reported but cannot be directly
measured or quantified. Nevertheless, a suite of biomarkers related to mechanisms, neural …

Our understanding of chronic pain involves complex brain circuits that include sensory,
emotional, cognitive and interoceptive processing. The feed-forward interactions between …

Persistent and disabling pain is the hallmark of osteoarthritis, rheumatoid arthritis,
fibromyalgia, and various other rheumatologic conditions. However, disease severity (as …

Affective experiences are commonly represented by either transient emotional reactions to
discrete events or longer term, sustained mood states that are characterized by a more …

Models describing the neural correlates of biased emotion processing in depression have
focused on increased activation of anterior cingulate and amygdala and decreased …