Ethnopharmacological relevance Baicalin (BI) is an important biologically active flavonoid
isolated from the root of Scutellaria radix (Huang Qin). Traditionally Scutellaria radix was the …

Interleukin-33 (IL-33) is a nuclear factor mainly expressed in barrier epithelium, endothelial
cells, and fibroblast reticular cells. Some inflammatory cells also express IL-33 under certain …

Pain is a cardinal feature of many diseases. Chronic pain poses heavy burdens to the
suffering patients, both physically and mentally. However, current mainstream medications …

Gout is a disease caused by uric acid (UA) accumulation in the joints, causing inflammation.
Two UA forms–monosodium urate (MSU) and soluble uric acid (sUA) have been shown to …

Introduction: To explore the relationship between the composite dietary antioxidant index
(CDAI) and gout to provide support for preventing gout through dietary intervention …

Cancer-induced bone pain (CIBP) is a type of ongoing or breakthrough pain caused by a
primary bone tumor or bone metastasis. CIBP constitutes a specific pain state with distinct …

Rheumatoid arthritis (RA) is a chronic autoimmune disease that occurs mainly in synovial
joints, causing synovial inflammation and joint injury. If diagnosed and treated in time, the …

Acute gouty arthritis is a self-limiting inflammatory disease resulting from the deposition of
monosodium urate (MSU) crystals. It has been shown that Gentiopicroside (GPS) possesses …

Background Acute gouty arthritis is inflammatory joint arthritis. Gouty arthritis (GA) involves
multiple pathological processes. Deposition of joints by monosodium urate (MSU) crystals …

Pain is a main symptom in inflammation, and inflammation induces pain via inflammatory
mediators acting on nociceptive neurons. Macrophages and microglia are distinct cell types …