An evaluation of chloroquine as a broad-acting antiviral against hand, foot and mouth disease

YW Tan, WK Yam, J Sun, JJH Chu - Antiviral research, 2018 - Elsevier
A common childhood affliction of viral origin in young children and immunocompromised
adults, the Hand, Foot and Mouth Disease (HFMD) has become a significant public health …

Virus shedding in patients with hand, foot and mouth disease induced by EV71, CA16 or CA6: systematic review and meta-analysis

X Duan, Z Chen, X Li, P Yuan… - The Pediatric Infectious …, 2021 - journals.lww.com
Background: As the highly contagious hand, foot and mouth disease (HFMD) spreads
rapidly among children, isolation is the most effective way to control its spread. However …

The clinical and epidemiological study of children with hand, foot, and mouth disease in Hunan, China from 2013 to 2017

J Qiu, H Yan, N Cheng, X Lu, X Hu, L Liang, Z Xiao… - Scientific reports, 2019 - nature.com
Hand, foot, and mouth disease (HFMD) is endemic in the Pacific region, especially in
mainland China. The case-fatality ratio of HFMD is increasing steadily. Knowledge of the …

Changing serotypes of hand, foot and mouth disease in Shanghai, 2017–2019

L Hu, H Maimaiti, L Zhou, J Gao, Y Lu - Gut Pathogens, 2022 - Springer
Background Hand, foot, and mouth disease (HFMD) is a common reportable infectious
disease that is highly contagious among children in China. This study aimed to characterize …

Early warning of hand, foot, and mouth disease transmission: a modeling study in mainland, China

J Rui, K Luo, Q Chen, D Zhang, Q Zhao… - PLoS neglected …, 2021 - journals.plos.org
Background Hand, foot, and mouth disease (HFMD) is a global infectious disease;
particularly, it has a high disease burden in China. This study was aimed to explore the …

Epidemiology of 45,616 suspect cases of hand, foot and mouth disease in Chongqing, China, 2011–2015

J Tao, X He, Y Shi, G Zhu, S Liu, Z Zhang, S Tang… - Scientific Reports, 2017 - nature.com
Epidemiology and etiology of hand, foot, and mouth disease (HFMD) based on large sample
size or evaluation of detection for more enterovirus serotypes are not well investigated in …

Characterization of an inactivated whole-virus bivalent vaccine that induces balanced protective immunity against coxsackievirus A6 and A10 in mice

Z Zhang, Z Dong, Q Wang, MJ Carr, J Li, T Liu, D Li… - Vaccine, 2018 - Elsevier
Abstract Coxsackievirus A6 (CVA6) and CVA10 are two of the major pathogens associated
with hand, foot and mouth disease (HFMD) in children. The majority of CVA6 and CVA10 …

Non-linear association between daily mean temperature and children's hand foot and mouth disease in Chongqing, China

L Yang, T Liu, D Tian, H Zhao, Y Xia, J Wang, T Li… - Scientific Reports, 2023 - nature.com
Chongqing was seriously affected by hand, foot, and mouth disease (HFMD), but the
relationships between daily mean temperature and the incidence of HFMD remain unclear …

[HTML][HTML] A Potential Use of Vidarabine: Alleviation of Functional Constipation Through Modulation of the Adenosine A2A Receptor-MLC Signaling Pathway and the …

X Gao, K Guo, S Liu, W Yang, J Sheng, Y Tian… - International Journal of …, 2024 - mdpi.com
Vidarabine (VID) is an antiviral medication that is commonly utilized to treat conditions such
as hand, foot, and mouth disease and herpes. Constipation is a prevalent complication of …

Study of integrated protective immunity induced in rhesus macaques by the intradermal administration of a bivalent EV71-CA16 inactivated vaccine

S Fan, Y Liao, G Jiang, L Jiang, L Wang, X Xu, M Feng… - Vaccine, 2020 - Elsevier
Abstract Enterovirus type 71 (EV71) and coxsackievirus A 16 (CA16) are recognized as the
major pathogens responsible for human hand-foot-mouth disease. To develop a bivalent …