Post-COVID-19 depressive symptoms: epidemiology, pathophysiology, and pharmacological treatment

MG Mazza, M Palladini, S Poletti, F Benedetti - CNS drugs, 2022 - Springer
Abstract The Coronavirus Disease 2019 (COVID-19) pandemic is still spreading worldwide
over 2 years since its outbreak. The psychopathological implications in COVID-19 survivors …

Interleukin‐6 blocking agents for treating COVID‐19: a living systematic review

L Ghosn, R Assi, T Evrenoglou… - Cochrane database …, 2023 - cochranelibrary.com
Background It has been reported that people with COVID‐19 and pre‐existing
autoantibodies against type I interferons are likely to develop an inflammatory cytokine storm …

Melatonin–Microbiome two-sided interaction in Dysbiosis-associated conditions

MI Iesanu, CDM Zahiu, IA Dogaru, DM Chitimus… - Antioxidants, 2022 - mdpi.com
Melatonin is a pineal indolamine, allegedly known as a circadian rhythm regulator, and an
antioxidative and immunomodulatory molecule. In both experimental and clinical trials …

Does evidence exist to blunt inflammatory response by nutraceutical supplementation during covid-19 pandemic? An overview of systematic reviews of vitamin d …

S Corrao, R Mallaci Bocchio, M Lo Monaco, G Natoli… - Nutrients, 2021 - mdpi.com
More than one year has passed since the first cases of coronavirus disease 2019 (COVID-
19) caused by severe acute respiratory syndrome (SARS)-CoV-2 coronavirus were reported …

Melatonin: highlighting its use as a potential treatment for SARS-CoV-2 infection

RJ Reiter, R Sharma, F Simko… - Cellular and Molecular …, 2022 - Springer
Numerous pharmaceutical drugs have been repurposed for use as treatments for COVID-19
disease. These drugs have not consistently demonstrated high efficacy in preventing or …

[HTML][HTML] Natural ingredients to improve immunity

A Gasmi, M Shanaida, O Oleshchuk, Y Semenova… - Pharmaceuticals, 2023 - mdpi.com
The immune system protects the body from infectious agents such as bacteria, viruses, or
fungi. Once encountered with pathogens or antigens, the innate and adaptive arms of the …

Efficacy of melatonin in the treatment of patients with COVID‐19: a systematic review and meta‐analysis of randomized controlled trials

SH Lan, HZ Lee, CM Chao, SP Chang… - Journal of medical …, 2022 - Wiley Online Library
This study investigated the effect of melatonin on clinical outcomes in patients with
coronavirus disease 2019 (COVID‐19). We searched PubMed, the Web of Science, the …

Melatonin and related compounds: antioxidant and anti-inflammatory actions

M Bantounou, J Plascevic, HF Galley - Antioxidants, 2022 - mdpi.com
Melatonin, an indoleamine derived from tryptophan and produced in the pineal gland and
other tissues [1, 2] is a potent antioxidant and inflammatory agent [1]. Specifically, the …

The role of interleukin-22 in lung health and its therapeutic potential for COVID-19

S Fang, D Ju, Y Lin, W Chen - Frontiers in immunology, 2022 - frontiersin.org
Although numerous clinical trials have been implemented, an absolutely effective treatment
against coronavirus disease 2019 (COVID-19) is still elusive. Interleukin-22 (IL-22) has …

The importance of sleep and circadian rhythms for vaccination success and susceptibility to viral infections

NCM Schmitz, YD van der Werf… - Clocks & sleep, 2022 - mdpi.com
Sleep and circadian rhythms are closely involved in the immune system and its regulation.
Here, we describe this relationship and provide recommendations regarding the influence of …