Chemokines are small proteins that control several tissue functions, including cell
recruitment and activation under homeostatic and inflammatory conditions. CXCL8 …

Pain is one of the most challenging symptoms for patients with rheumatoid arthritis (RA). RA-
related pain is frequently considered to be solely a consequence of inflammation in the …

Objective Host–microbial interactions are central in health and disease. Monosodium urate
monohydrate (MSU) crystals cause gout by activating the NLRP3 inflammasome, leading to …

Background Obstructive sleep apnea (OSA) is characterized by recurrent nocturnal hypoxia
and sleep disruption. Sleep fragmentation caused hyperalgesia in volunteers, while …

Objective To evaluate the role of neutrophil extracellular traps (NETs) in the genesis of joint
hyperalgesia using an experimental model of arthritis and transpose the findings to clinical …

Rheumatoid arthritis (RA) and periodontal disease (PD) are prevalent chronic inflammatory
disorders that affect bone structures. Individuals with RA are more likely to experience PD …

Gout is a self‐limited inflammatory disease caused by deposition of monosodium urate
(MSU) crystals in the joints. Resolution of inflammation is an active process leading to …

Septic arthritis is an inflammatory joint disease that is induced by pathogens such as
Staphylococcus aureus. Infection of the joint triggers an acute inflammatory response …

Biochanin A (BCA) is a natural organic compound of the class of phytochemicals known as
flavonoids and isoflavone subclass predominantly found in red clover (Trifolium pratense). It …

Methyl gallate (MG) is a prevalent phenolic acid in the plant kingdom, and its presence in
herbal medicines might be related to its remarkable biological effects, such as its …