Extensive scientific investigations in recent decades have established the anatomical,
biomechanical, and functional importance that the meniscus holds within the knee joint. As a …

Collagen is the most widely distributed class of proteins in the human body. The use of
collagen-based biomaterials in the field of tissue engineering applications has been …

Meniscus injuries are prevalent in orthopedic diagnosis. The reconstruction of the structural
inhomogeneity and anisotropy of the meniscus is a major challenge in clinical practice …

Decellularization is the process of removing the cellular components from tissues or organs.
It is a promising technology for obtaining a biomaterial with a highly preserved extracellular …

The reconstruction of musculoskeletal defects is a constant challenge for orthopaedic
surgeons. Musculoskeletal injuries such as fractures, chondral lesions, infections and tumor …

Decellularized materials (DMs) are attracting more and more attention because of their
native structures, comparatively high bioactivity, low immunogenicity and good …

Importance of the field: Biomimetic scaffolds and substrates of extracellular matrices (ECMs)
play an important role in the regulation of cell function and in the guidance of new tissue …

Tissue-derived extracellular matrix (ECM) biomaterials to regenerate the meniscus have
gained increasing attention in treating meniscus injuries and diseases, particularly for aged …

Damage of cartilage structures in the head and neck region as well as in orthopedic sites
are frequently caused by trauma, tumor resection, or congenital defects. Despite a high …

Decellularization is the process by which cells are discharged from tissues/organs, but all of
the essential cues for cell preservation and homeostasis are retained in a three-dimensional …