Interstitial lung disease
KM Antoniou, GA Margaritopoulos… - European …, 2014 - Eur Respiratory Soc
Interstitial lung diseases are a group of diffuse parenchymal lung disorders associated with
substantial morbidity and mortality. Knowledge achieved in recent years has resulted in the …
substantial morbidity and mortality. Knowledge achieved in recent years has resulted in the …
Etiologies of sarcoidosis
ES Chen, DR Moller - Clinical reviews in allergy & immunology, 2015 - Springer
Since sarcoidosis was first described more than a century ago, the etiologic determinants
causing this disease remain uncertain. Studies suggest that genetic, host immunologic, and …
causing this disease remain uncertain. Studies suggest that genetic, host immunologic, and …
Definition and consensus diagnostic criteria for neurosarcoidosis: from the neurosarcoidosis consortium consensus group
BJ Stern, W Royal, JM Gelfand, DB Clifford… - JAMA …, 2018 - jamanetwork.com
Importance The Neurosarcoidosis Consortium Consensus Group, an expert panel of
physicians experienced in the management of patients with sarcoidosis and …
physicians experienced in the management of patients with sarcoidosis and …
[HTML][HTML] Tofacitinib treatment and molecular analysis of cutaneous sarcoidosis
W Damsky, D Thakral, N Emeagwali… - New England Journal …, 2018 - Mass Medical Soc
There is evidence that Janus kinase (JAK)–signal transducer and activator of transcription
(STAT) signaling plays a role in the pathogenesis of sarcoidosis. We treated a patient with …
(STAT) signaling plays a role in the pathogenesis of sarcoidosis. We treated a patient with …
Janus kinase inhibition induces disease remission in cutaneous sarcoidosis and granuloma annulare
W Damsky, D Thakral, MK McGeary, J Leventhal… - Journal of the American …, 2020 - Elsevier
Background Sarcoidosis and granuloma annulare (GA) are cutaneous granulomatous
disorders that can be difficult to treat. There is evidence of underlying Janus kinase (JAK) …
disorders that can be difficult to treat. There is evidence of underlying Janus kinase (JAK) …
Genetic, immunologic, and environmental basis of sarcoidosis
DR Moller, BA Rybicki, NY Hamzeh… - Annals of the …, 2017 - atsjournals.org
Sarcoidosis is a multisystem disease with tremendous heterogeneity in disease
manifestations, severity, and clinical course that varies among different ethnic and racial …
manifestations, severity, and clinical course that varies among different ethnic and racial …
The pathogenesis of pulmonary sarcoidosis and implications for treatment
KC Patterson, ES Chen - Chest, 2018 - Elsevier
Thoracic sarcoidosis is the most common form of sarcoidosis, encompassing a
heterogeneous group of patients with a wide range of clinical features and associated …
heterogeneous group of patients with a wide range of clinical features and associated …
Diagnosis of sarcoidosis
TE Wessendorf, F Bonella, U Costabel - Clinical reviews in allergy & …, 2015 - Springer
The diagnosis of sarcoidosis, a systemic granulomatous disease, is based on a compatible
clinical–radiological picture and the histological evidence of noncaseating granulomas …
clinical–radiological picture and the histological evidence of noncaseating granulomas …
Blockade of the Programmed Death-1 Pathway Restores Sarcoidosis CD4+ T-Cell Proliferative Capacity
NA Braun, LJ Celada, JD Herazo-Maya… - American journal of …, 2014 - atsjournals.org
Rationale: Effective therapeutic interventions for chronic, idiopathic lung diseases remain
elusive. Normalized T-cell function is an important contributor to spontaneous resolution of …
elusive. Normalized T-cell function is an important contributor to spontaneous resolution of …
Treatment of multiorgan sarcoidosis with tofacitinib
Objective Sarcoidosis is an idiopathic inflammatory disorder that is difficult to treat. There is
accumulating evidence that constitutive activation of Janus kinase–signal transducer and …
accumulating evidence that constitutive activation of Janus kinase–signal transducer and …