Applications of amyloid, tau, and neuroinflammation PET imaging to Alzheimer's disease and mild cognitive impairment
Alzheimer's disease (AD) is a devastating and progressive neurodegenerative disease for
which there is no cure. Mild cognitive impairment (MCI) is considered a prodromal stage of …
which there is no cure. Mild cognitive impairment (MCI) is considered a prodromal stage of …
Recent update on the heterogeneity of the Alzheimer's disease spectrum
KA Jellinger - Journal of Neural Transmission, 2022 - Springer
Abstract Alzheimer's disease (AD), the most common form of dementia worldwide, is a mixed
proteinopathy (β-amyloid, tau and other proteins). Classically defined as a …
proteinopathy (β-amyloid, tau and other proteins). Classically defined as a …
Distinct tau PET patterns in atrophy‐defined subtypes of Alzheimer's disease
R Ossenkoppele, CH Lyoo, CH Sudre… - Alzheimer's & …, 2020 - Wiley Online Library
Introduction Differential patterns of brain atrophy on structural magnetic resonance imaging
(MRI) revealed four reproducible subtypes of Alzheimer's disease (AD):(1)“typical”,(2)“limbic …
(MRI) revealed four reproducible subtypes of Alzheimer's disease (AD):(1)“typical”,(2)“limbic …
Characterization of the logopenic variant of primary progressive aphasia: a systematic review and meta-analysis
The linguistic and anatomical variability of the logopenic variant of Primary Progressive
Aphasia (lv-PPA) as defined by current diagnostic criteria has been the topic of an intense …
Aphasia (lv-PPA) as defined by current diagnostic criteria has been the topic of an intense …
Pathobiological subtypes of Alzheimer disease
KA Jellinger - Dementia and Geriatric Cognitive Disorders, 2021 - karger.com
Alzheimer disease (AD), the most common form of dementia, is a heterogenous disorder
with various pathobiological subtypes. In addition to the 4 major subtypes based on the …
with various pathobiological subtypes. In addition to the 4 major subtypes based on the …
Tau and amyloid relationships with resting-state functional connectivity in atypical Alzheimer's disease
The mechanisms through which tau and amyloid-beta (Aβ) accumulate in the brain of
Alzheimer's disease patients may differ but both are related to neuronal networks. We …
Alzheimer's disease patients may differ but both are related to neuronal networks. We …
Longitudinal neuroimaging biomarkers differ across Alzheimer's disease phenotypes
Alzheimer's disease can present clinically with either the typical amnestic phenotype or with
atypical phenotypes, such as logopenic progressive aphasia and posterior cortical atrophy …
atypical phenotypes, such as logopenic progressive aphasia and posterior cortical atrophy …
[HTML][HTML] Tau covariance patterns in Alzheimer's disease patients match intrinsic connectivity networks in the healthy brain
According to the network model of neurodegeneration, the spread of pathogenic proteins
occurs selectively along connected brain regions. We tested in vivo whether the distribution …
occurs selectively along connected brain regions. We tested in vivo whether the distribution …
Neuropathological assessment of the Alzheimer spectrum
KA Jellinger - Journal of Neural Transmission, 2020 - Springer
Alzheimer disease (AD), the most common form of dementia globally, classically defined a
clinicopathological entity, is a heterogenous disorder with various pathobiological subtypes …
clinicopathological entity, is a heterogenous disorder with various pathobiological subtypes …
Regional multimodal relationships between tau, hypometabolism, atrophy, and fractional anisotropy in atypical Alzheimer's disease
I Sintini, CG Schwarz, PR Martin… - Human brain …, 2019 - Wiley Online Library
Alzheimer's disease (AD) can present with atypical clinical forms where the prominent
domain of deficit is not memory, that is, atypical AD. Atypical AD patients show cortical …
domain of deficit is not memory, that is, atypical AD. Atypical AD patients show cortical …