Leveraging zebrafish to study retinal degenerations
JM Angueyra, KS Kindt - Frontiers in cell and developmental biology, 2018 - frontiersin.org
Retinal degenerations are a heterogeneous group of diseases characterized by death of
photoreceptors and progressive loss of vision. Retinal degenerations are a major cause of …
photoreceptors and progressive loss of vision. Retinal degenerations are a major cause of …
Neural mechanisms of motion processing in the mammalian retina
W Wei - Annual review of vision science, 2018 - annualreviews.org
Visual motion on the retina activates a cohort of retinal ganglion cells (RGCs). This
population activity encodes multiple streams of information extracted by parallel retinal …
population activity encodes multiple streams of information extracted by parallel retinal …
In vivo measurement of afferent activity with axon-specific calcium imaging
In vivo calcium imaging from axons provides direct interrogation of afferent neural activity,
informing the neural representations that a local circuit receives. Unlike in somata and …
informing the neural representations that a local circuit receives. Unlike in somata and …
Zebrafish differentially process color across visual space to match natural scenes
MJY Zimmermann, NE Nevala, T Yoshimatsu, D Osorio… - Current Biology, 2018 - cell.com
Animal eyes have evolved to process behaviorally important visual information, but how
retinas deal with statistical asymmetries in visual space remains poorly understood. Using …
retinas deal with statistical asymmetries in visual space remains poorly understood. Using …
The dynamic receptive fields of retinal ganglion cells
S Wienbar, GW Schwartz - Progress in retinal and eye research, 2018 - Elsevier
Retinal ganglion cells (RGCs) were one of the first classes of sensory neurons to be
described in terms of a receptive field (RF). Over the last six decades, our understanding of …
described in terms of a receptive field (RF). Over the last six decades, our understanding of …
Functional compartmentalization within starburst amacrine cell dendrites in the retina
A Poleg-Polsky, H Ding, JS Diamond - Cell reports, 2018 - cell.com
Dendrites in many neurons actively compute information. In retinal starburst amacrine cells,
transformations from synaptic input to output occur within individual dendrites and mediate …
transformations from synaptic input to output occur within individual dendrites and mediate …
Current methods to investigate nociception and pain in zebrafish
N Ohnesorge, C Heinl, L Lewejohann - Frontiers in Neuroscience, 2021 - frontiersin.org
Pain is an unpleasant, negative emotion and its debilitating effects are complex to manage.
Mammalian models have long dominated research on nociception and pain, but there is …
Mammalian models have long dominated research on nociception and pain, but there is …
Neural mechanisms generating orientation selectivity in the retina
P Antinucci, O Suleyman, C Monfries, R Hindges - Current Biology, 2016 - cell.com
The orientation of visual stimuli is a salient feature of visual scenes. In vertebrates, the first
neural processing steps generating orientation selectivity take place in the retina. Here, we …
neural processing steps generating orientation selectivity take place in the retina. Here, we …
General features of the retinal connectome determine the computation of motion anticipation
J Johnston, L Lagnado - Elife, 2015 - elifesciences.org
Motion anticipation allows the visual system to compensate for the slow speed of
phototransduction so that a moving object can be accurately located. This correction is …
phototransduction so that a moving object can be accurately located. This correction is …
A retinal circuit generating a dynamic predictive code for oriented features
J Johnston, SH Seibel, LSA Darnet, S Renninger… - Neuron, 2019 - cell.com
Sensory systems must reduce the transmission of redundant information to function
efficiently. One strategy is to continuously adjust the sensitivity of neurons to suppress …
efficiently. One strategy is to continuously adjust the sensitivity of neurons to suppress …