Potential Protective Role Exerted by Secoiridoids from Olea europaea L. in Cancer, Cardiovascular, Neurodegenerative, Aging-Related, and Immunoinflammatory …

ML Castejón, T Montoya, C Alarcón-de-la-Lastra… - Antioxidants, 2020 - mdpi.com
Iridoids, which have beneficial health properties, include a wide group of cyclopentane [c]
pyran monoterpenoids present in plants and insects. The cleavage of the cyclopentane ring …

Effects of oleuropein and hydroxytyrosol on inflammatory mediators: Consequences on inflammaging

F Pojero, A Aiello, F Gervasi, C Caruso… - International Journal of …, 2022 - mdpi.com
Aging is associated with a low-grade, systemic inflammatory state defined as
“inflammaging”, ruled by the loss of proper regulation of the immune system leading to the …

Nootkatone confers antifibrotic effect by regulating the TGF-β/Smad signaling pathway in mouse model of unilateral ureteral obstruction

S Gairola, C Ram, AM Syed, P Doye, U Kulhari… - European Journal of …, 2021 - Elsevier
Chronic kidney disease (CKD) with underlying interstitial fibrosis is often associated with
end-stage renal disease (ESRD). In the present study, we investigated the renoprotective …

The contribution of the immune system to genitourinary fibrosis

KM Doersch, D Barnett, A Chase… - Experimental …, 2022 - journals.sagepub.com
Fibrotic diseases of the genitourinary tract are devastating and incompletely understood
pathologies. These diseases include urethral and ureteral strictures, retroperitoneal fibrosis …

The pivotal role of oleuropein in the anti-diabetic action of the mediterranean diet: A concise review

A Da Porto, G Brosolo, V Casarsa, L Bulfone… - Pharmaceutics, 2021 - mdpi.com
Type 2 diabetes currently accounts for more than 90% of all diabetic patients. Lifestyle
interventions and notably dietary modifications are one of the mainstays for the prevention …

Retinoprotective effect of wild olive (Acebuche) oil-enriched diet against ocular oxidative stress induced by arterial hypertension

Á Santana-Garrido, C Reyes-Goya, MC Pérez-Camino… - Antioxidants, 2020 - mdpi.com
Oxidative stress plays an important role in the pathogenesis of ocular diseases, including
hypertensive eye diseases. The beneficial effects of olive oil on cardiovascular diseases …

Calcium dobesilate prevents cisplatin-induced nephrotoxicity by modulating oxidative and histopathological changes in mice

G Bazmandegan, I Fatemi, A Kaeidi… - Naunyn-Schmiedeberg's …, 2021 - Springer
Cisplatin is one of the synthetic cancer medicines with nephrotoxicity being one of its major
side effects. Past research shows that calcium dobesilate (CaD), as a vascular protective …

Health benefits of olive oil and by-products and possible innovative applications for industrial processes

M Centrone, M Ranieri, A Di Mise, M D'Agostino… - Functional Foods in …, 2021 - ffhdj.com
In the last few years, the production of olive oil has incredibly increased due to its beneficial
properties on human health. On the other hand, the amount of waste and by-products …

Unilateral ureteral obstruction for 28 days in rats is not associated with changes in cardiac function or alterations in mitochondrial function

R Prieto-Carrasco, A Silva-Palacios, P Rojas-Morales… - Biology, 2021 - mdpi.com
Simple Summary This work shows that renal damage produced by the demonstration of
unilateral ureteral obstruction (UUO) is not related to cardiac dysfunction or the change in …

Ameliorative effects of oleuropein on lipopolysaccharide-induced acute lung injury model in rats

N Dikmen, M Cellat, M Etyemez, CT İşler, A Uyar… - Inflammation, 2021 - Springer
Acute lung injury (ALI) is one of the most common causes of death in diseases with septic
shock. Oleuropein, one of the important components of olive leaf, has antioxidant and anti …