What is new on ovarian carcinoma: integrated morphologic and molecular analysis following the new 2020 World Health Organization classification of female genital …

A De Leo, D Santini, C Ceccarelli, G Santandrea… - Diagnostics, 2021 - mdpi.com
Ovarian carcinomas represent a heterogeneous group of neoplasms consisting of separate
entities with distinct risk factors, precursor lesions, pathogenesis, patterns of spread …

[HTML][HTML] Molecular characteristics and clinical behaviour of epithelial ovarian cancers

RL Hollis - Cancer letters, 2023 - Elsevier
Ovarian carcinoma (OC) is an umbrella term for multiple distinct diseases (histotypes), each
with their own developmental origins, clinical behaviour and molecular profile. Accordingly …

Distinct transcriptional programs stratify ovarian cancer cell lines into the five major histological subtypes

BM Barnes, L Nelson, A Tighe, GJ Burghel, IH Lin… - Genome Medicine, 2021 - Springer
Background Epithelial ovarian cancer (OC) is a heterogenous disease consisting of five
major histologically distinct subtypes: high-grade serous (HGSOC), low-grade serous …

Endometriosis-associated ovarian carcinomas: how PI3K/AKT/mTOR pathway affects their pathogenesis

TS Driva, C Schatz, J Haybaeck - Biomolecules, 2023 - mdpi.com
Ovarian clear cell (OCCC) and endometrioid (EnOC) carcinomas are often subsumed under
the umbrella term “endometriosis-associated ovarian cancer”(EAOC), since they frequently …

Molecular stratification of endometrioid ovarian carcinoma predicts clinical outcome

RL Hollis, JP Thomson, B Stanley… - Nature …, 2020 - nature.com
Endometrioid ovarian carcinoma (EnOC) demonstrates substantial clinical and molecular
heterogeneity. Here, we report whole exome sequencing of 112 EnOC cases following …

An aptamer‐based nanoflow cytometry method for the molecular detection and classification of ovarian cancers through profiling of tumor markers on small …

J Li, Y Li, Q Li, L Sun, Q Tan, L Zheng… - Angewandte Chemie …, 2024 - Wiley Online Library
Molecular profiling of protein markers on small extracellular vesicles (sEVs) is a promising
strategy for the precise detection and classification of ovarian cancers. However, this …

[HTML][HTML] An integrated molecular profile of endometrioid ovarian cancer

WE Pierson, PN Peters, MT Chang, L Chen… - Gynecologic …, 2020 - Elsevier
Objective Endometrioid ovarian carcinoma (EOVC) is an uncommon subtype of epithelial
ovarian carcinoma and its molecular characteristics have been incompletely described. Prior …

Mismatch repair deficiency in ovarian carcinoma: frequency, causes, and consequences

S Leskela, I Romero, E Cristobal… - The American Journal …, 2020 - journals.lww.com
Mismatch repair deficiency (MMRD) is involved in the initiation of both hereditary and
sporadic tumors. MMRD has been extensively studied in colorectal cancer and endometrial …

Causality and functional relevance of BRCA1 and BRCA2 pathogenic variants in non‐high‐grade serous ovarian carcinomas

CJH Kramer, L Lanjouw, D Ruano… - The Journal of …, 2024 - Wiley Online Library
The identification of causal BRCA1/2 pathogenic variants (PVs) in epithelial ovarian
carcinoma (EOC) aids the selection of patients for genetic counselling and treatment …

Endometrial cancer molecular risk stratification is equally prognostic for endometrioid ovarian carcinoma

P Krämer, A Talhouk, MA Brett, DS Chiu, ES Cairns… - Clinical Cancer …, 2020 - AACR
Purpose: Endometrioid ovarian carcinoma (ENOC) is generally associated with a more
favorable prognosis compared with other ovarian carcinomas. Nonetheless, current patient …