Oxidative cyclization in natural product biosynthesis

MC Tang, Y Zou, K Watanabe, CT Walsh… - Chemical …, 2017 - ACS Publications
Oxidative cyclizations are important transformations that occur widely during natural product
biosynthesis. The transformations from acyclic precursors to cyclized products can afford …

Fe (II)/α-ketoglutarate-dependent hydroxylases and related enzymes

RP Hausinger - Critical reviews in biochemistry and molecular …, 2004 - Taylor & Francis
Fe (II)/α-ketoglutarate (αKG)-dependent hydroxylases catalyze an amazing diversity of
reactions that result in protein side-chain modifications, repair of alkylated DNA/RNA …

Biosynthesis of medicinal tropane alkaloids in yeast

P Srinivasan, CD Smolke - Nature, 2020 - nature.com
Tropane alkaloids from nightshade plants are neurotransmitter inhibitors that are used for
treating neuromuscular disorders and are classified as essential medicines by the World …

[图书][B] Flavonoids: chemistry, biochemistry and applications

OM Andersen, KR Markham - 2005 - taylorfrancis.com
Advances in the flavonoid field have been nothing short of spectacular over the last 20
years. While the medical field has noticed flavonoids for their potential antioxidant …

Evolution and diversity of the 2–oxoglutarate‐dependent dioxygenase superfamily in plants

Y Kawai, E Ono, M Mizutani - The Plant Journal, 2014 - Wiley Online Library
Summary The 2–oxoglutarate‐dependent dioxygenase (2 OGD) superfamily is the second
largest enzyme family in the plant genome, and its members are involved in various …

Alkaloid biosynthesis: metabolism and trafficking

J Ziegler, PJ Facchini - Annu. Rev. Plant Biol., 2008 - annualreviews.org
Alkaloids represent a highly diverse group of compounds that are related only by the
occurrence of a nitrogen atom in a heterocyclic ring. Plants are estimated to produce …

ALKALOID BIOSYNTHESIS IN PLANTS: Biochemistry, Cell Biology, Molecular Regulation, and Metabolic Engineering Applications

PJ Facchini - Annual review of plant biology, 2001 - annualreviews.org
▪ Abstract Recent advances in the cell, developmental, and molecular biology of alkaloid
biosynthesis have heightened our appreciation for the complexity and importance of plant …

[图书][B] Alkaloids-Secrets of Life:: Aklaloid Chemistry, Biological Significance, Applications and Ecological Role

T Aniszewski - 2007 - books.google.com
Alkaloids, represent a group of interesting and complex chemical compounds, produced by
the secondary metabolism of living organisms in different biotopes. They are relatively …

Unusual dioxygen-dependent reactions catalyzed by nonheme iron enzymes in natural product biosynthesis

R Ushimaru, I Abe - ACS Catalysis, 2022 - ACS Publications
Nonheme iron-dependent enzymatic reactions play crucial roles in building and modifying
bioactive organic molecules in all major classes of natural product pathways. While the …

Alkaloid Biosynthesis [mdash] The Basis for Metabolic Engineering of Medicinal Plants.

TM Kutchan - The plant cell, 1995 - ncbi.nlm.nih.gov
Alkaloids-the term is linguistically derived from the Arabic word a/-qali, the plant from which
soda was first obtainedare nitrogenous compounds that constitute the pharmacologically …