Cold atmospheric plasma mediated cell membrane permeation and gene delivery-empirical interventions and pertinence

PR Sreedevi, K Suresh - Advances in Colloid and Interface Science, 2023 - Elsevier
Delivery of genetic material to cells is an integral tool to analyze and reveal the genetic
interventions in normal cellular processes and differentiation, disease development and for …

Electroporation-based therapy for brain tumors: a review

Z Fang, L Chen, MAJ Moser… - Journal of …, 2021 - asmedigitalcollection.asme.org
Abstract Electroporation-based therapy (EBT), as a high-voltage-pulse technology has been
prevalent with favorable clinical outcomes in the treatment of various solid tumors. This …

Effects of solution conductivity on macropore size dynamics in electroporated lipid vesicle membranes

E Sabri, M Aleksanyan, C Brosseau, R Dimova - Bioelectrochemistry, 2022 - Elsevier
Using fast imaging microscopy, we investigate in detail the expansion of micron-sized pores
occurring in individual electroporated giant unilamellar vesicles composed of the …

[PDF][PDF] 微/纳秒脉冲电场靶向不同尺寸肿瘤细胞内外膜电穿孔效应研究

姚陈果, 宁郡怡, 刘红梅, 郑爽, 董守龙 - 电工技术学报, 2020 - dgjsxb.ces-transaction.com
摘要为深入研究细胞物理特性对微/纳秒脉冲电场诱导的电穿孔效应差异,
以三种不同细胞大小及两种不同细胞核大小的肿瘤细胞为研究对象, 基于其细胞几何特征建立1 …

Advanced biotechnology for cell cryopreservation

J Yang, L Gao, M Liu, X Sui, Y Zhu, C Wen… - Transactions of Tianjin …, 2020 - Springer
Cell cryopreservation has evolved as an important technology required for supporting
various cell-based applications, such as stem cell therapy, tissue engineering, and assisted …

Multiphysics modelling of electroporation under uni-or bipolar nanosecond pulse sequences

F Guo, K Qian, L Zhang, X Liu, H Peng - Bioelectrochemistry, 2021 - Elsevier
A nonlinear dispersive multiphysics model of single-cell electroporation was proposed in
this paper. The time-domain Debye model was utilised to describe the membrane dispersion …

A coupled model of electroporation and electrodeformation considering dynamic Young's modulus

F Guo, Z Luo, J Xiang - Applied Physics Letters, 2023 - pubs.aip.org
Cells exposed to a pulsed electric field undergo electrodeformation (ED) and electroporation
(EP) under the action of electric field stress, and this paper proposes a coupled model of EP …

In vitro experimental and numerical studies on the preferential ablation of chemo-resistant tumor cells induced by high-voltage nanosecond pulsed electric fields

H Liu, C Yao, Y Zhao, X Chen, S Dong… - IEEE Transactions …, 2020 - ieeexplore.ieee.org
Chemoresistance causes tumor recurrence and metastasis, resulting in poor clinical
outcomes and low survival, and has been considered an obstacle to tumor therapy. The …

Multiphysics analysis of nsPEF induced electrodeformation in a dispersive cell model

F Guo, K Qian, H Deng, X Li - Applied Physics Letters, 2021 - pubs.aip.org
Exposed to the nanosecond pulsed electric field (nsPEF), biological cells can be stretched in
the direction parallel to the electric field direction. A multiphysics model to investigate …

A single-cell electroporation model for quantitatively estimating the pore area ratio by high-frequency irreversible electroporation

L Ding, Z Fang, MAJ Moser, W Zhang, B Zhang - Applied Sciences, 2023 - mdpi.com
Featured Application Electroporation-based techniques, eg, tumor ablation, cardiac ablation,
bacterial decontamination, gene electrotransfer, and electrochemotherapy. Abstract The …