Metabolic Profile, Bioactivities, and Variations in the Chemical Constituents of Essential Oils of the Ferula Genus (Apiaceae)

P Sonigra, M Meena - Frontiers in pharmacology, 2021 - frontiersin.org
The genus Ferula is the third largest and a well-known genus of the Apiaceae family. It is
categorized in the Peucedaneae tribe and Ferulinae subtribe of the Apiaceae family. At …

Natural products: a promising therapeutics for targeting tumor angiogenesis

R Li, X Song, Y Guo, P Song, D Duan… - Frontiers in oncology, 2021 - frontiersin.org
Tumor-associated angiogenesis is a key target for anti-cancer therapy. The imbalance
between pro-angiogenic and anti-angiogenic signals elicited by tumor cells or tumor …

Fabrication and assessment of folic acid conjugated-chitosan modified PLGA nanoparticle for delivery of alpha terpineol in colon cancer

A Rahmati, M Homayouni Tabrizi… - Journal of Biomaterials …, 2022 - Taylor & Francis
The objective of this study was to fabrication of α-terpineol-PLGA nanoparticles coated with
folic acid-chitosan (αT-PCF-NPs) as well as evaluates their anticancer effects. αT-PCF-NPs …

Modulation of hypoxia-inducible factor-1 signaling pathways in cancer angiogenesis, invasion, and metastasis by natural compounds: a comprehensive and critical …

S Fakhri, SZ Moradi, F Faraji, L Kooshki… - Cancer and Metastasis …, 2024 - Springer
Tumor cells employ multiple signaling mediators to escape the hypoxic condition and trigger
angiogenesis and metastasis. As a critical orchestrate of tumorigenic conditions, hypoxia …

Antiangiogenic effects of coumarins against cancer: From chemistry to medicine

MB Majnooni, S Fakhri, A Smeriglio, D Trombetta… - Molecules, 2019 - mdpi.com
Angiogenesis, the process of formation and recruitment of new blood vessels from pre-
existing vessels, plays an important role in the development of cancer. Therefore, the use of …

Folic acid conjugated-chitosan modified nanostructured lipid carriers as promising carriers for delivery of Umbelliprenin to cancer cells: In vivo and in vitro

F Sadeghzadeh, A Motavalizadehkakhky… - European Polymer …, 2023 - Elsevier
The aim of this survey was to load Umbelliprenin (UMB) on nanostructured lipid carriers
(NLCs) coated with folic acid-bound chitosan and to investigate its anti-cancer effects in vitro …

Preparation and characterization of the myricetin-loaded solid lipid nanoparticles decorated with folic acid-bound chitosan and evaluation of its antitumor and anti …

N Khatamian, A Motavalizadehkakhky… - Cancer …, 2023 - Springer
Myricetin is a flavonoid with anticancer properties. This study aimed to formulate myricetin in
the form of solid lipid nanoparticles (SLN), decorated with chitosan (CS) and active-targeted …

Vascular mimicry: A potential therapeutic target in breast cancer

H Chavoshi, N Poormolaie, V Vahedian… - … -Research and Practice, 2022 - Elsevier
Treating breast cancer, especially in the invasive state, is one of the challenges in treating
cancer. Invasion and metastasis are factors in the failure of breast cancer treatments. One of …

An overview of lipoxygenase inhibitors with approach of in vivo studies

A Orafaie, M Mousavian, H Orafai… - Prostaglandins & Other …, 2020 - Elsevier
Lipoxygenases (LOXs) are enzymes which found in organisms that catalyze the
peroxidation of polyunsaturated fatty acids (Arachidonic acid, Linoleic acid). The key role of …

Effect of folic acid‐linked chitosan‐coated PLGA‐based curcumin nanoparticles on the redox system of glioblastoma cancer cells

N Ghoreyshi, A Ghahremanloo, H Javid… - Phytochemical …, 2023 - Wiley Online Library
Objectives Oxidative stress is one of the carcinogenic mechanisms underlying the
development of glioblastoma multiforme (GBM), a highly aggressive brain tumor type …