[HTML][HTML] What do we not know about mitochondrial potassium channels?

M Laskowski, B Augustynek, B Kulawiak… - … et Biophysica Acta (BBA …, 2016 - Elsevier
In this review, we summarize our knowledge about mitochondrial potassium channels, with
a special focus on unanswered questions in this field. The following potassium channels …

Ion channels in microbes

B Martinac, Y Saimi, C Kung - Physiological reviews, 2008 - journals.physiology.org
Studies of ion channels have for long been dominated by the animalcentric, if not
anthropocentric, view of physiology. The structures and activities of ion channels had …

Structure of TRPV1 channel revealed by electron cryomicroscopy

VY Moiseenkova-Bell, LA Stanciu… - Proceedings of the …, 2008 - National Acad Sciences
The transient receptor potential (TRP) family of ion channels participate in many signaling
pathways. TRPV1 functions as a molecular integrator of noxious stimuli, including heat, low …

Molecular architecture and subunit organization of TRPA1 ion channel revealed by electron microscopy

TL Cvetkov, KW Huynh, MR Cohen… - Journal of Biological …, 2011 - ASBMB
Transient receptor potential ankyrin 1 (TRPA1) is a non-selective ion channel, which is
expressed in nociceptor sensory neurons and transduces chemical, inflammatory, and …

Evolution of the human ion channel set

TJ Jegla, CM Zmasek, S Batalov… - … chemistry & high …, 2009 - ingentaconnect.com
Ion channels are intimately involved in virtually every physiological process of consequence
in humans. Their importance is underscored by the identification of numerous …

Hybrid polymer–lipid films as platforms for directed membrane protein insertion

J Kowal, D Wu, V Mikhalevich, CG Palivan, W Meier - Langmuir, 2015 - ACS Publications
Hybrids composed of amphiphilic block copolymers and lipids constitute a new generation
of biological membrane-inspired materials. Hybrid membranes resulting from self-assembly …

Classification of structural heterogeneity by maximum-likelihood methods

SHW Scheres - Methods in enzymology, 2010 - Elsevier
With the advent of computationally feasible approaches to maximum-likelihood (ML) image
processing for cryo-electron microscopy, these methods have proven particularly useful in …

A 3.5-nm structure of rat TRPV4 cation channel revealed by Zernike phase-contrast cryoelectron microscopy

H Shigematsu, T Sokabe, R Danev, M Tominaga… - Journal of Biological …, 2010 - ASBMB
The transient receptor potential vanilloid 4 (TRPV4) is a non-selective cation channel
responsive to various stimuli including cell swelling, warm temperatures (27–35° C), and …

Applications of high-speed atomic force microscopy to real-time visualization of dynamic biomolecular processes

T Uchihashi, S Scheuring - Biochimica et Biophysica Acta (BBA)-General …, 2018 - Elsevier
Background Many biological processes in a living cell are consequences of sequential and
hierarchical dynamic events of biological macromolecules such as molecular interactions …

Ligand discrimination and gating in cyclic nucleotide-gated ion channels from apo and partial agonist-bound cryo-EM structures

J Rheinberger, X Gao, PAM Schmidpeter… - Elife, 2018 - elifesciences.org
Cyclic nucleotide-modulated channels have important roles in visual signal transduction and
pacemaking. Binding of cyclic nucleotides (cAMP/cGMP) elicits diverse functional responses …