Increased Cerebral Level of P2X7R in a Tauopathy Mouse Model by PET Using [18F]GSK1482160
Y Kong, L Cao, J Wang, J Zhuang, Y Liu… - ACS chemical …, 2024 - ACS Publications
Neuroinflammation plays an important role in Alzheimer's disease and primary tauopathies.
The aim of the current study was to map [18F] GSK1482160 for imaging of purinergic P2X7R …
The aim of the current study was to map [18F] GSK1482160 for imaging of purinergic P2X7R …
[HTML][HTML] Myricetin ameliorates cognitive impairment in 3× Tg Alzheimer's disease mice by regulating oxidative stress and tau hyperphosphorylation
L Wang, Z Tang, B Li, Y Peng, X Yang, Y Xiao… - Biomedicine & …, 2024 - Elsevier
Background Alzheimer's disease is characterized by abnormal β-amyloid (Aβ) plaque
accumulation, tau hyperphosphorylation, reactive oxidative stress, mitochondrial dysfunction …
accumulation, tau hyperphosphorylation, reactive oxidative stress, mitochondrial dysfunction …
In vivo reactive astrocyte imaging using [18F] SMBT-1 in tauopathy and familial Alzheimer's disease mouse models: A multi-tracer study
Y Kong, L Cao, J Wang, J Zhuang, F Xie, C Zuo… - Journal of the …, 2024 - Elsevier
Background Reactive astrocytes play an important role in the development of Alzheimer's
disease and primary tauopathies. Here, we aimed to investigate the relationships between …
disease and primary tauopathies. Here, we aimed to investigate the relationships between …
Hippocampal mGluR5 levels are comparable in Alzheimer′ s and control brains, and divergently influenced by amyloid and tau in control brain
J Wang, S Savodalli, Y Kong, C Mashio, U Konietzko… - bioRxiv, 2024 - biorxiv.org
Background: Metabotropic glutamate receptor 5 (mGluR5) modulates excitatory
glutamatergic synaptic transmission and plays an important role in learning and memory …
glutamatergic synaptic transmission and plays an important role in learning and memory …