microRNAs in action: biogenesis, function and regulation
Ever since microRNAs (miRNAs) were first recognized as an extensive gene family> 20
years ago, a broad community of researchers was drawn to investigate the universe of small …
years ago, a broad community of researchers was drawn to investigate the universe of small …
Regulation of microRNA biogenesis and its crosstalk with other cellular pathways
T Treiber, N Treiber, G Meister - Nature reviews Molecular cell biology, 2019 - nature.com
MicroRNAs (miRNAs) are short non-coding RNAs that inhibit the expression of target genes
by directly binding to their mRNAs. miRNAs are transcribed as precursor molecules, which …
by directly binding to their mRNAs. miRNAs are transcribed as precursor molecules, which …
MicroRNA biogenesis pathways in cancer
S Lin, RI Gregory - Nature reviews cancer, 2015 - nature.com
MicroRNAs (miRNAs) are critical regulators of gene expression. Amplification and
overexpression of individual'oncomiRs' or genetic loss of tumour suppressor miRNAs are …
overexpression of individual'oncomiRs' or genetic loss of tumour suppressor miRNAs are …
HBXIP-elevated methyltransferase METTL3 promotes the progression of breast cancer via inhibiting tumor suppressor let-7g
Abstract Methyltransferase-like 3 (METTL3) is involved in RNA metabolism through N6-
methyladenosine (m 6 A) modification. However, whether METTL3 participates in the …
methyladenosine (m 6 A) modification. However, whether METTL3 participates in the …
Transposable elements drive widespread expression of oncogenes in human cancers
Transposable elements (TEs) are an abundant and rich genetic resource of regulatory
sequences,–. Cryptic regulatory elements within TEs can be epigenetically reactivated in …
sequences,–. Cryptic regulatory elements within TEs can be epigenetically reactivated in …
An overview of microRNAs
SM Hammond - Advanced drug delivery reviews, 2015 - Elsevier
The discovery of the first microRNA (miRNA) over 20 years ago has ushered in a new era in
molecular biology. There are now over 2000 miRNAs that have been discovered in humans …
molecular biology. There are now over 2000 miRNAs that have been discovered in humans …
Regulation of microRNA biogenesis
M Ha, VN Kim - Nature reviews Molecular cell biology, 2014 - nature.com
MicroRNAs (miRNAs) are small non-coding RNAs that function as guide molecules in RNA
silencing. Targeting most protein-coding transcripts, miRNAs are involved in nearly all …
silencing. Targeting most protein-coding transcripts, miRNAs are involved in nearly all …
The LIN28/let-7 pathway in cancer
Among all tumor suppressor microRNAs, reduced let-7 expression occurs most frequently in
cancer and typically correlates with poor prognosis. Activation of either LIN28A or LIN28B …
cancer and typically correlates with poor prognosis. Activation of either LIN28A or LIN28B …
Epigenetic associations between lncRNA/circRNA and miRNA in hepatocellular carcinoma
Simple Summary Non-coding RNAs such as microRNAs, long non-coding RNAs, and
circular RNAs contribute to the development and progression of hepatocellular carcinoma …
circular RNAs contribute to the development and progression of hepatocellular carcinoma …
Neuroblastoma—a neural crest derived embryonal malignancy
JI Johnsen, C Dyberg, M Wickström - Frontiers in molecular …, 2019 - frontiersin.org
Neuroblastoma is a neural crest derived malignancy of the peripheral nervous system and is
the most common and deadliest tumor of infancy. It is characterized by clinical heterogeneity …
the most common and deadliest tumor of infancy. It is characterized by clinical heterogeneity …