Potential clinical applications of pro-resolving lipids mediators from docosahexaenoic acid

MP Beyer, LA Videla, C Farías, R Valenzuela - Nutrients, 2023 - mdpi.com
Docosahexaenoic acid (C22: 6 n-3, DHA) is the precursor of specialized pro-resolving lipid
mediators (SPMs), such as resolvin, protectin, and maresin families which have been …

Resolution pharmacology and the treatment of infectious diseases

VV Costa, F Resende, EM Melo… - British Journal of …, 2024 - Wiley Online Library
Inflammation is elicited by the host in response to microbes, and is believed to be essential
for protection against infection. However, we have previously hypothesized that excessive or …

Saliva metabolomic profile of COVID-19 patients associates with disease severity

N Saheb Sharif-Askari, NC Soares, HA Mohamed… - Metabolomics, 2022 - Springer
Abstract Introduction Coronavirus disease 2019 (COVID-19) is strongly linked to
dysregulation of various molecular, cellular, and physiological processes that change …

[HTML][HTML] Decreased oxidative stress and altered urinary oxylipidome by intravenous omega-3 fatty acid emulsion in a randomized controlled trial of older subjects …

SC Pawelzik, H Arnardottir, P Sarajlic, A Mahdi… - Free Radical Biology …, 2023 - Elsevier
Proinflammatory bioactive lipid mediators and oxidative stress are increased in coronavirus
disease 2019 (COVID-19). The randomized controlled single-blind trial COVID-Omega-F …

[HTML][HTML] Immunomodulation by intravenous omega‐3 fatty acid treatment in older subjects hospitalized for COVID‐19: a single‐blind randomized controlled trial

H Arnardottir, SC Pawelzik, P Sarajlic… - Clinical and …, 2022 - ncbi.nlm.nih.gov
Dear Editor, COVID-Omega-F (“Resolving inflammatory storm in COVID-19 patients by
Omega-3 Polyunsaturated fatty acids”) is a randomized controlled trial on intravenous (iv) …

COVID-19, blood lipid changes, and thrombosis

AA Farooqui, T Farooqui, GY Sun, TN Lin, DBL Teh… - Biomedicines, 2023 - mdpi.com
Although there is increasing evidence that oxidative stress and inflammation induced by
COVID-19 may contribute to increased risk and severity of thromboses, the underlying …

[HTML][HTML] The role of nutrition on the treatment of Covid 19

S Younes - Human Nutrition & Metabolism, 2024 - Elsevier
The rapid and extensive transmission of the SARS-CoV-2 virus has led to a worldwide
COVID-19 pandemic. Initially thought to be an acute illness, many patients have reported …

Prostaglandin E2/Leukotriene B4 balance and viral load in distinct clinical stages of COVID-19: A cross-sectional study

LR Gadelha, MJB Costa, JPA de Abreu… - Prostaglandins & Other …, 2024 - Elsevier
Abstract Background Prostaglandin E 2 (PGE 2) and leukotriene B 4 (LTB 4) are
eicosanoids involved in modulation of the antiviral immune response. Recent studies have …

Maresin: Macrophage Mediator for Resolving Inflammation and Bridging Tissue Regeneration—A System-Based Preclinical Systematic Review

WC Liu, YH Yang, YC Wang, WM Chang… - International journal of …, 2023 - mdpi.com
Maresins are lipid mediators derived from omega-3 fatty acids with anti-inflammatory and
pro-resolving properties, capable of promoting tissue regeneration and potentially serving …

Treatment of COVID-19 Pneumonia and Acute Respiratory Distress With Ramatroban, a Thromboxane A2 and Prostaglandin D2 Receptor Antagonist: A Four-Patient …

ML Ogletree, K Chander Chiang… - Frontiers in …, 2022 - frontiersin.org
Hypoxemia in COVID-19 pneumonia is associated with hospitalization, mechanical
ventilation, and mortality. COVID-19 patients exhibit marked increases in fatty acid levels …