Neurodegenerative diseases encompass a heterogeneous group of disorders that afflict
millions of people worldwide. Characteristic protein aggregates are histopathological …

Alzheimer's disease (AD) is a progressive neurodegenerative disease. The accumulation of
amyloid-β (Aβ) plaques and tau neurofibrillary tangles are the key players responsible for …

Depression is among the most common neuropsychiatric comorbidities in Alzheimer's
disease (AD) and other Tauopathies. Apart from its anti-depressive and anxiolytic effects …

The present investigation was designed based on the evidence that, in neurodegenerative
disorders, such as Alzheimer's dementia (AD) and Parkinson's disease (PD), damage to the …

Alzheimer's disease (AD) is a progressive degenerative disorder that results in a severe loss
of brain cells and irreversible cognitive decline. Memory problems are the most recognized …

Isolation of rodents throughout adolescence is known to induce many behavioral
abnormalities which resemble neuropsychiatric disorders. Separately, this paradigm has …

Alzheimer's disease (AD) is a lethal neurodegenerative disorder characterized by severe
brain pathologies and progressive cognitive decline. While the exact cause of this disease …

The impact of Alzheimer's disease (AD) and its related dementias is rapidly expanding, and
its mitigation remains an urgent social and technical challenge. To date there are no …

As the most common cause of dementia, Alzheimer's disease (AD) is characterized by
neurodegeneration and synaptic loss with an increasing prevalence in the elderly …

The orexin system is closely related to the pathogenesis of Alzheimer's disease (AD). Orexin-
A aggravates cognitive dysfunction and increases amyloid β (Aβ) deposition in AD model …