Engineering biological nanopore approaches toward protein sequencing

X Wei, T Penkauskas, JE Reiner, C Kennard… - ACS …, 2023 - ACS Publications
Biotechnological innovations have vastly improved the capacity to perform large-scale
protein studies, while the methods we have for identifying and quantifying individual proteins …

Single-molecular protein-based bioelectronics via electronic transport: fundamentals, devices and applications

T Jiang, BF Zeng, B Zhang, L Tang - Chemical Society Reviews, 2023 - pubs.rsc.org
Biomolecular electronics is a rapidly growing multidisciplinary field that combines biology,
nanoscience, and engineering to bridge the two important fields of life sciences and …

A Single‐Molecule Bioelectronic Portable Array for Early Diagnosis of Pancreatic Cancer Precursors

E Genco, F Modena, L Sarcina, K Björkström… - Advanced …, 2023 - Wiley Online Library
A cohort of 47 patients is screened for pancreatic cancer precursors with a portable 96‐well
bioelectronic sensing‐array for single‐molecule assay in cysts fluid and blood plasma …

Convection driven ultrarapid protein detection via nanobody‐functionalized organic electrochemical transistors

A Koklu, S Wustoni, K Guo, R Silva… - Advanced …, 2022 - Wiley Online Library
Conventional biosensors rely on the diffusion‐dominated transport of the target analyte to
the sensor surface. Consequently, they require an incubation step that may take several …

A handheld intelligent single-molecule binary bioelectronic system for fast and reliable immunometric point-of-care testing

E Macchia, ZM Kovács-Vajna, D Loconsole… - Science …, 2022 - science.org
Molecular tests are highly reliable and sensitive but lack portability and are not simple to
use; conversely, easy-to-use antigenic tests still lack high performance. BioScreen combines …

Reduced Graphene Oxide Electrolyte‐Gated Transistor Immunosensor with Highly Selective Multiparametric Detection of Anti‐Drug Antibodies

M Sensi, RF de Oliveira, M Berto, M Palmieri… - Advanced …, 2023 - Wiley Online Library
The advent of immunotherapies with biological drugs has revolutionized the treatment of
cancers and auto‐immune diseases. However, in some patients, the production of anti‐drug …

Point‐Of‐Care Ultra‐Portable Single‐Molecule Bioassays for One‐Health

E Macchia, F Torricelli, M Caputo, L Sarcina… - Advanced …, 2024 - Wiley Online Library
Screening asymptomatic organisms (humans, animals, plants) with a high‐diagnostic
accuracy using point‐of‐care‐testing (POCT) technologies, though still visionary holds great …

Carbon nanotube field-effect transistor biosensor with an enlarged gate area for ultra-sensitive detection of a lung cancer biomarker

L Li, X Liu, T Wei, K Wang, Z Zhao, J Cao… - … Applied Materials & …, 2023 - ACS Publications
Carcinoembryonic antigen (CEA) is a recognized biomarker for lung cancer and can be
used for early detection. However, the clinical value of CEA is not fully realized due to the …

A universal bacterial sensor created by integrating a light modulating aptamer complex with photoelectrochemical signal readout

F Bakhshandeh, S Saha, P Sen, S Sakib… - Biosensors and …, 2023 - Elsevier
Photoelectrochemical (PEC) signal transduction is of great interest for ultrasensitive
biosensing; however, signal-on PEC assays that do not require target labeling remain …

Biosensors for Public Health and Environmental Monitoring: The Case for Sustainable Biosensing

A Williams, MR Aguilar… - ACS Sustainable …, 2024 - ACS Publications
Climate change is a profound crisis that affects every aspect of life, including public health.
Changes in environmental conditions can promote the spread of pathogens and the …